SCHEMBL5084751

SCHEMBL5084751

C1=CC(c2ccc([SiH2]c3ccc(C4C=Cc5ccccc54)cc3)cc2)c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.33
HTR2A P28223 1/20 0.33
PRCP P42785 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2830664 0.85 PRCP (0.39) HTR6HTR2APRCP
SCHEMBL1028466 0.82 HTR2A (0.39) HTR6HTR2A
SCHEMBL9145143 0.80 HTR2A (0.38) HTR6HTR2A
SCHEMBL9145856 0.80 HTR2A (0.38) HTR6HTR2A
Ammonia Solution, Strong SCHEMBL21245914 0.80 HTR2A (0.38) HTR6HTR2A
Methane SCHEMBL28813011 0.80 HTR2A (0.38) HTR6HTR2A
SCHEMBL9145850 0.80 HTR2A (0.38) HTR6HTR2A
Lithium SCHEMBL9145147 0.80 HTR2A (0.38) HTR6HTR2A
SCHEMBL7091333 0.79 HTR6 (0.53) HTR6HTR2A
SCHEMBL15814999 0.79 KDM1A (0.37) HTR6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1753796-A1 MULTIPLE CATALYST AND REACTOR SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) 2007-02-21 EP claimed
WO-2005113622-A1 MULTIPLE CATALYST AND REACTOR SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-12-01 WO claimed
EP-1954724-A1 SYNDIOTACTIC PROPYLENE ELASTOMERS ExxonMobil Chemical Patents Inc. (US) 2008-08-13 EP disclosed
WO-2007061525-A1 SYNDIOTACTIC PROPYLENE ELASTOMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-31 WO disclosed
EP-0376154-B2 Bisindenyl derivative and method for its preparation TARGOR GMBH (DE) 2000-09-27 EP disclosed
EP-0768320-A1 Catalyst component and catalyst NIPPON OIL CO. LTD. (JP) 1997-04-16 EP disclosed
EP-0718323-A2 Ethylene type quaternary copolymer rubber SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-06-26 EP disclosed
EP-0692486-A2 Bisindenyl derivative and process for its preparation HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-17 EP disclosed
EP-0376154-A2 Bisindenyl derivative and method for its preparation HOECHST AKTIENGESELLSCHAFT (DE) 1990-07-04 EP disclosed