SCHEMBL5084860

SCHEMBL5084860

FC(F)(F)c1ccccc1O[Zr]1(Oc2ccccc2C(F)(F)F)C2C(=CC3=C2CCCC3)CCC2=CC3=C(CCCC3)C21

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.32
PTGS2 P35354 1/20 0.32
HTR1A P08908 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5084879 0.83 HTR1A (0.32) HTR1ASLC6A2SLC6A4SLC6A3
SCHEMBL5497453 0.77 SLC6A2 (0.34) HTR1ASLC6A2SLC6A4SLC6A3
SCHEMBL5084915 0.77 LTA4H (0.32) LTA4H
SCHEMBL5081382 0.75
SCHEMBL5084197 0.69 ALDH1A1 (0.33)
SCHEMBL4459287 0.63
SCHEMBL4452832 0.63
SCHEMBL62839 0.63
SCHEMBL8979292 0.63
SCHEMBL1685381 0.62 LTA4H (0.46) LTA4HPTGS2HTR1ASLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7345119-B2 Olefin polymerization catalyst and olefin polymerization method using the same MARUZEN PETROCHEMICAL COMPANY, LIMITED (JP) 2008-03-18 US disclosed
US-20050215736-A1 Olefin polymerization catalyst and olefin polymerization method using the same MARUZEN PETROCHEMICAL COMPANY, LIMITED (JP) 2005-09-29 US disclosed
EP-1541598-A1 Olefin polymerization catalyst and olefin polymerization method using the same MARUZEN PETROCHEMICAL CO., LTD. (JP) 2005-06-15 EP disclosed