Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490255 | 1.00 | THRB (0.49) | THRBATMALDH1A1MAPTMEN1 | |
| SCHEMBL490211 | 0.84 | THRB (0.53) | THRBATMALDH1A1MAPTMEN1 | |
| SCHEMBL490210 | 0.84 | THRB (0.53) | THRBATMALDH1A1MAPTMEN1 | |
| SCHEMBL7119159 | 0.82 | THRB (0.39) | THRBATMALDH1A1MAPTMEN1 | |
| SCHEMBL9556877 | 0.81 | THRB (0.40) | THRBATMALDH1A1MAPTMEN1 | |
| SCHEMBL19183552 | 0.81 | THRB (0.40) | THRBATMALDH1A1MAPTMEN1 | |
| SCHEMBL16266990 | 0.80 | THRB (0.51) | THRBATMALDH1A1MAPTMEN1 | |
| SCHEMBL16266993 | 0.80 | THRB (0.51) | THRBATMALDH1A1MAPTMEN1 | |
| SCHEMBL8523376 | 0.79 | THRB (0.43) | THRBATMALDH1A1MAPTMEN1 | |
| SCHEMBL8523379 | 0.79 | THRB (0.43) | THRBATMALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008079898-A1 | METHODS AND TOPICAL FORMULATIONS COMPRISING COLLOIDAL METAL FOR TREATING OR PREVENTING SKIN CONDITIONS | PHARMWEST, INC. (US) | 2008-07-03 | — | — | WO | disclosed |
| EP-0359488-A2 | A composition of matter | NEUTROGENA CORPORATION (US) | 1990-03-21 | — | — | EP | disclosed |