⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2761711 | 0.83 | MEN1 (0.32) | — | |
| SCHEMBL322239 | 0.80 | MEN1 (0.35) | — | |
| SCHEMBL8855149 | 0.80 | MEN1 (0.35) | — | |
| SCHEMBL11552312 | 0.74 | — | — | |
| SCHEMBL115447 | 0.74 | CYP3A4 (0.33) | — | |
| SCHEMBL14976825 | 0.74 | C1R (0.36) | — | |
| SCHEMBL9729872 | 0.73 | — | — | |
| SCHEMBL335714 | 0.73 | MEN1 (0.37) | — | |
| SCHEMBL981109 | 0.73 | TSHR (0.39) | — | |
| SCHEMBL769410 | 0.73 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417252-B1 | HIGH REFRACTIVE INDEX POLYSILOXANES AND THEIR PREPARATION | DOW CORNING (US) | 2015-07-01 | — | — | EP | disclosed |
| EP-2782565-A1 | USE OF ARYL AND HETARYL CARBOXAMIDES AS ENDOPARASITICIDES | Bayer Intellectual Property GmbH (DE) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013076230-A1 | USE OF ARYL AND HETARYL CARBOXAMIDES AS ENDOPARASITICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-30 | — | — | WO | disclosed |
| US-7429638-B2 | High refractive index polysiloxanes and their preparation | DOW CORNING LIMITED (GB) | 2008-09-30 | — | — | US | disclosed |
| US-20040236057-A1 | High refractive index polysiloxanes and their preparation | DOW SILICONES CORPORATION | 2004-11-25 | — | — | US | disclosed |
| US-20040138399-A1 | Preparation of silicone resins | DOW CORNING CORPORATION | 2004-07-15 | — | — | US | disclosed |
| EP-1417252-A2 | HIGH REFRACTIVE INDEX POLYSILOXANES AND THEIR PREPARATION | Dow Corning Corporation (US) | 2004-05-12 | — | — | EP | disclosed |
| EP-1383823-A1 | PREPARATION OF SILICONE RESINS | Dow Corning Corporation (US) | 2004-01-28 | — | — | EP | disclosed |
| WO-2003011944-A2 | HIGH REFRACTIVE INDEX POLYSILOXANES AND THEIR PREPARATION | DOW CORNING CORPORATION (US) | 2003-02-13 | — | — | WO | disclosed |
| US-6472392-B1 | Triazole compounds and the use thereof as dopamine-D3 -ligands | ABBOTT LABORATORIES | 2002-10-29 | — | — | US | disclosed |
| WO-2002081552-A1 | PREPARATION OF SILICONE RESINS | DOW CORNING CORPORATION (US) | 2002-10-17 | — | — | WO | disclosed |
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |
| US-5116732-A | Chromagens for Histological Staining | FISHER SCIENTIFIC CO. (US) | 1992-05-26 | — | — | US | disclosed |
| US-4895587-A | Haloacetamide compounds, process for production thereof, and use thereof as herbicide | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1990-01-23 | — | — | US | disclosed |
| EP-0206251-B1 | HALOACETAMIDE COMPOUNDS, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDE | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1988-09-07 | — | — | EP | disclosed |
| EP-0206251-A1 | Haloacetamide compounds, process for production thereof, and use thereof as herbicide | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1986-12-30 | — | — | EP | disclosed |