SCHEMBL5086230

SCHEMBL5086230

CCCCC(C(=O)OCC)C(CC)OC(=O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
LMNA P02545 4/20 0.44
NPC1 O15118 2/20 0.43
ALDH1A1 P00352 2/20 0.43
CA2 P00918 1/20 0.43
CYP3A4 P08684 1/20 0.43
TDP1 Q9NUW8 2/20 0.41
PRKCA P17252 1/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40
RAB9A P51151 1/20 0.40
TSHR P16473 3/20 0.40
TP53 P04637 1/20 0.40
ALOX12 P18054 1/20 0.39
KDM4E B2RXH2 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5082210 0.92 MEN1 (0.44) MEN1KMT2ALMNANPC1ALDH1A1
SCHEMBL5085827 0.92 LMNA (0.46) MEN1KMT2ALMNANPC1ALDH1A1
SCHEMBL5085898 0.88 NPC1 (0.49) MEN1KMT2ALMNANPC1ALDH1A1
SCHEMBL5082120 0.85 LMNA (0.45) MEN1KMT2ALMNANPC1ALDH1A1
SCHEMBL5085964 0.85 LMNA (0.47) MEN1KMT2ALMNANPC1ALDH1A1
SCHEMBL5082885 0.84 LMNA (0.46) MEN1KMT2ALMNANPC1ALDH1A1
SCHEMBL5082107 0.83 MMP8 (0.47) MEN1KMT2ALMNANPC1ALDH1A1
SCHEMBL5079895 0.83 KMT2A (0.44) MEN1KMT2ALMNANPC1ALDH1A1
SCHEMBL17965791 0.82 MEN1 (0.49) MEN1KMT2ALMNAALDH1A1CA2
SCHEMBL14690219 0.82 MEN1 (0.49) MEN1KMT2ALMNAALDH1A1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1690039-A Diester compound for preparing olefinic polymerization catalyst SINOPEC CORP (CN) 2005-11-02 CN claimed
EP-1746110-B1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2015-03-11 EP disclosed
CN-101759816-B Method for preparing a catalyst component for olefinic polymerization, and a catalyst component thereof CHINA PETROLEUM & CHEMICAL 2012-05-30 CN disclosed
CN-101759816-A Method for preparing a catalyst component for olefinic polymerization, and a catalyst component thereof CHINA PETROLEUM & CHEMICAL 2010-06-30 CN disclosed
CN-100429243-C Method for preparing catalyst constituent for olefinic polymerization CHINA PETROCHEMICAL CO LTD (CN) 2008-10-29 CN disclosed
CN-100429242-C Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2008-10-29 CN disclosed
US-7351778-B2 Catalyst component for olefin polymerization and catalyst comprising the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-04-01 US disclosed
CN-100348624-C Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2007-11-14 CN disclosed
EP-1746110-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF China Petroleum & Chemical Corporation (CN) 2007-01-24 EP disclosed
CN-1891722-A Method for preparing catalyst constituent for olefinic polymerization CHINA PETROCHEMICAL CO LTD (CN) 2007-01-10 CN disclosed
US-20060287446-A1 Catalyst component for olefin polymerization and catalyst comprising the same BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CHINA PETROLEUM & CHEMICAL COPORATION (CN) 2006-12-21 US disclosed
CN-1282670-C Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2006-11-01 CN disclosed
CN-1803863-A Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2006-07-19 CN disclosed
CN-1803862-A Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2006-07-19 CN disclosed
CN-1690039-A Diester compound for preparing olefinic polymerization catalyst SINOPEC CORP (CN) 2005-11-02 CN disclosed
CN-1690090-A Catalyst components for olefinic polyreaction and catalyst thereof SINOPEC CORP (CN) 2005-11-02 CN disclosed