Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996333 | 0.86 | MEN1 (0.53) | HPGDHSP90AA1HSP90AB1MEN1KMT2A | |
| SCHEMBL8996312 | 0.82 | TTR (0.71) | HPGDHSP90AA1HSP90AB1MEN1KMT2A | |
| SCHEMBL5088188 | 0.81 | CYP1A2 (0.48) | KEAP1HPGDHSP90AA1HSP90AB1MEN1 | |
| SCHEMBL8996338 | 0.81 | MEN1 (0.55) | HPGDHSP90AA1HSP90AB1MEN1KMT2A | |
| SCHEMBL8996342 | 0.79 | ELANE (0.49) | HPGDHSP90AA1HSP90AB1MEN1KMT2A | |
| SCHEMBL26187353 | 0.75 | TTR (0.54) | KEAP1MEN1KMT2AALDH1A1TTR | |
| SCHEMBL30609982 | 0.75 | TTR (0.54) | KEAP1MEN1KMT2AALDH1A1TTR | |
| SCHEMBL9877831 | 0.75 | HTR1A (0.50) | MEN1KMT2AALDH1A1CYP1A2HTR1A | |
| SCHEMBL8947495 | 0.75 | EGFR (0.73) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL15413441 | 0.75 | MEN1 (0.49) | HPGDHSP90AA1HSP90AB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008090078-A1 | METHOD FOR THE SYNTHESIS OF RHEIN AND DERIVATIVES THEREOF | PIERRE FABRE MEDICAMENT (FR) | 2008-07-31 | — | — | WO | disclosed |