SCHEMBL5085963

SCHEMBL5085963

CCCCCCN(CCCCCC)c1ccc(Nc2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.55
KCNH2 Q12809 1/20 0.51
ALDH1A1 P00352 5/20 0.48
HTT P42858 3/20 0.48
RAB9A P51151 2/20 0.48
LMNA P02545 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
HPGD P15428 2/20 0.47
ALOX12 P18054 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MGLL Q99685 1/20 0.43
POLB P06746 2/20 0.43
RECQL P46063 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
NPC1 O15118 1/20 0.42
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3691462 0.91 MAPT (0.64) MAPTKCNH2ALDH1A1HTTLMNA
SCHEMBL3979891 0.91 MAPT (0.64) MAPTKCNH2ALDH1A1HTTLMNA
SCHEMBL5835749 0.85 MAPT (0.73) MAPTKCNH2ALDH1A1HTTLMNA
SCHEMBL9358488 0.83 MAPT (0.55) MAPTKCNH2ALDH1A1RAB9ALMNA
SCHEMBL592174 0.83 MAPT (0.55) MAPTKCNH2ALDH1A1RAB9ALMNA
SCHEMBL9358492 0.83 MAPT (0.55) MAPTKCNH2ALDH1A1RAB9ALMNA
SCHEMBL592173 0.83 MAPT (0.55) MAPTKCNH2ALDH1A1RAB9ALMNA
SCHEMBL10947692 0.82 RAB9A (0.62) MAPTALDH1A1RAB9ALMNAHPGD
SCHEMBL9362320 0.82 MAPT (0.56) MAPTKCNH2ALDH1A1RAB9ALMNA
SCHEMBL9362316 0.82 MAPT (0.56) MAPTKCNH2ALDH1A1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2009082-B1 Synergistic lubricating oil composition containing a mixture of a nitro-substituted diarylamine and a diarylamine CHEVRON ORONITE CO (US) 2017-08-30 EP disclosed
EP-2009082-B1 Synergistic lubricating oil composition containing a mixture of a nitro-substituted diarylamine and a diarylamine CHEVRON ORONITE CO (US) 2017-08-30 EP disclosed
US-7683017-B2 Synergistic lubricating oil composition containing a mixture of a nitro-substituted diarylamine and a diarylamine CHEVRON ORONITE COMPANY LLC (US) 2010-03-23 US disclosed
US-7683017-B2 Synergistic lubricating oil composition containing a mixture of a nitro-substituted diarylamine and a diarylamine CHEVRON ORONITE COMPANY LLC (US) 2010-03-23 US disclosed
EP-2009082-A2 Synergistic lubricating oil composition containing a mixture of a nitro-substituted diarylamine and a diarylamine Chevron Oronite Company LLC (US) 2008-12-31 EP disclosed
EP-2009082-A2 Synergistic lubricating oil composition containing a mixture of a nitro-substituted diarylamine and a diarylamine Chevron Oronite Company LLC (US) 2008-12-31 EP disclosed
US-20080318815-A1 SYNERGISTIC LUBRICATING OIL COMPOSITION CONTAINING A MIXTURE OF A NITRO-SUBSTITUTED DIARYLAMINE AND A DAIRYLAMINE CHEVRON ORONITE COMPANY LLC 2008-12-25 US disclosed
US-20080318815-A1 SYNERGISTIC LUBRICATING OIL COMPOSITION CONTAINING A MIXTURE OF A NITRO-SUBSTITUTED DIARYLAMINE AND A DAIRYLAMINE CHEVRON ORONITE COMPANY LLC 2008-12-25 US disclosed
EP-0069585-B1 COLOR-FORMING SULFONAMIDODIPHENYLAMINES, PHOTOGRAPHIC ELEMENTS CONTAINING THEM AND CORRESPONDING SULFONIMIDE DYES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-07-03 EP disclosed
US-4499304-A COLOR PHOTOGRAPHY;SILVER HALIDE EMULSIONS; PRINTING PLATES; IMAGES EASTMAN KODAK COMPANY (US) 1985-02-12 US disclosed
US-4390606-A Color-forming para-sulfonamidodiphenylamine dye precursor and sulfonimide dye in photographic material and process EASTMAN KODAK COMPANY (US) 1983-06-28 US disclosed
EP-0069585-A1 Color-forming sulfonamidodiphenylamines, photographic elements containing them and corresponding sulfonimide dyes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-01-12 EP disclosed