SCHEMBL5086256

SCHEMBL5086256

CCCCC1=C(c2[c]c3c(cc2)-c2ccccc2C3)CC=C1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.32
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3444458 0.77 CYP1A2 (0.30)
SCHEMBL215716 0.74 NPC1 (0.36) SIGMAR1NPC1RAB9A
SCHEMBL217921 0.72 PNMT (0.36) NPC1RAB9A
SCHEMBL27316095 0.72 ELANE (0.35)
SCHEMBL4765918 0.71 CYP1A2 (0.41) NPC1RAB9A
SCHEMBL216506 0.71 NPC1 (0.35) SIGMAR1NPC1RAB9A
SCHEMBL218347 0.70 GPR3 (0.37) SIGMAR1NPC1RAB9A
SCHEMBL2972878 0.70 GPR3 (0.37) SIGMAR1NPC1RAB9A
SCHEMBL216547 0.70 GPR3 (0.37) SIGMAR1NPC1RAB9A
SCHEMBL215849 0.70 GPR3 (0.37) SIGMAR1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1283223-B1 Use of a mixture of two metallocene regioisomers as catalyst component for preparing bimodal isotactic polyolefins TOTAL PETROCHEMICALS RES FELUY (BE) 2008-04-09 EP disclosed
EP-1163278-B1 USE AND PRODUCTION OF POLYPROPYLENE TOTAL PETROCHEMICALS RES FELUY (BE) 2007-01-10 EP disclosed
US-20040249094-A1 Use and production of polypropylene ATOFINA RESEARCH, S.A. (BE) 2004-12-09 US disclosed
EP-1169356-B1 POLYOLEFIN PRODUCTION ATOFINA RES (BE) 2004-07-14 EP disclosed
CN-1152056-C Polyolefin production ���з����о���˾ 2004-06-02 CN disclosed
US-6727332-B2 SPECIFIC METALLOCENE CATALYSTS USED TO PREPARE PROPYLENE POLYMERS WITH LOW MELTING TEMPERATURE, HIGH CRYSTALLISATION TEMPERATURE AND HIGH TRANSPARENCY; HIGH SPEED SOLIDIFICATION FROM MELT ATOFINA RESEARCH S.A. (BE) 2004-04-27 US disclosed
EP-1283223-A2 Polyolefin production ATOFINA Research (BE) 2003-02-12 EP disclosed
US-6515086-B1 A process for preparing polyolefins having a monomer length of up to C10, which comprises first contacting: (1) a metallocene catalyst component for the preparation of a polyolefin which comprises an isotactic polyolefin or FINA RESEARCH, S.A. (BE) 2003-02-04 US disclosed
US-20020120080-A1 Use and production of polypropylene ATOFINA RESEARCH, S.A. (BE) 2002-08-29 US disclosed
EP-1031582-A1 Use and production of polypropylene FINA RESEARCH S.A. (BE) 2000-08-30 EP disclosed
EP-0881236-A1 Metallocene catalyst component for use in producing isotactic polyolefins FINA RESEARCH S.A. (BE) 1998-12-02 EP disclosed