Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5086256 | 0.77 | SIGMAR1 (0.32) | — | |
| SCHEMBL8369890 | 0.73 | PNMT (0.41) | CYP1A2ADRA2AMAOASLC6A2HTR2C | |
| SCHEMBL312235 | 0.72 | SRD5A2 (0.33) | CYP1A2ADRA2AMAOASLC6A2HTR2C | |
| SCHEMBL217877 | 0.71 | ALDH1A1 (0.36) | CYP1A2ADRA2AMAOASLC6A2HTR2C | |
| SCHEMBL216860 | 0.70 | ALDH1A1 (0.38) | CYP1A2ADRA2AMAOASLC6A2HTR2C | |
| SCHEMBL7708872 | 0.70 | KDM4E (0.31) | — | |
| SCHEMBL2974521 | 0.68 | KDM4E (0.36) | CYP1A2MAOA | |
| SCHEMBL2965677 | 0.68 | ALDH1A1 (0.36) | CYP1A2MAOA | |
| SCHEMBL313500 | 0.68 | PNMT (0.44) | CYP1A2MAOAHTR2CHTR2B | |
| SCHEMBL2964503 | 0.68 | CASP1 (0.37) | MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2277928-B1 | Shear thinning ethylene/alpha-olefin interpolymers and their preparation | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-02-21 | — | — | EP | disclosed |
| US-9045569-B2 | Process of making modified metallocene catalyst, catalyst produced and use thereof | W. R. GRACE & CO.-CONN. (US) | 2015-06-02 | — | — | US | disclosed |
| EP-1392741-B1 | PROCESS FOR PREPARING SUPPORTED TRANSITION METAL CATALYST SYSTEMS AND CATALYST SYSTEMS PREPARED THEREBY | GRACE W R & CO (US) | 2014-06-25 | — | — | EP | disclosed |
| US-20130289227-A1 | PROCESS OF MAKING MODIFIED METALLOCENE CATALYST, CATALYST PRODUCED AND USE THEREOF | W.R. GRACE & CO.-CONN (US) | 2013-10-31 | — | — | US | disclosed |
| EP-1242478-B1 | METALLOCENE AND CONSTRAINED GEOMETRY CATALYST SYSTEMS EMPLOYING AGGLOMERATED METAL OXIDE/CLAY SUPPORT-ACTIVATOR AND METHOD OF THEIR PREPARATION | GRACE W R & CO (US) | 2012-12-05 | — | — | EP | disclosed |
| US-7750104-B2 | E.g.., ethylene-ethylidenenorbornene-propylene terpolymer, characterized by a Processing Rheology Ratio of at least 8; the polymers do not include a traditional branch-inducing monomer such as norbornadiene; prepared without H2 using a constrained geometry complex catalyst and an activating cocatalyst | Dow Global Technologie Inc. (US) | 2010-07-06 | — | — | US | disclosed |
| US-7491672-B2 | Chemically-modified supports and supported catalyst systems prepared therefrom | INEOS EUROPE LIMITED (GB) | 2009-02-17 | — | — | US | disclosed |
| US-20080051531-A1 | GAS PHASE PROCESS FOR POLYMERS WITH GROUP 4 METAL COMPLEX CATALYST ADDITION | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2008-02-28 | — | — | US | disclosed |
| US-20070203314-A1 | E.g.., ethylene-ethylidenenorbornene-propylene terpolymer, characterized by a Processing Rheology Ratio of at least 8; the polymers do not include a traditional branch-inducing monomer such as norbornadiene; prepared without H2 using a constrained geometry complex catalyst and an activating cocatalyst | DUPONT DOW ELASTOMERS, LLC | 2007-08-30 | — | — | US | disclosed |
| US-7217676-B2 | Hydrophobization and silica for supported catalyst | EXXON MOBIL CHEMICAL PATENTS INC. (US) | 2007-05-15 | — | — | US | disclosed |
| WO-1997035893-A1 | HIGHLY SOLUBLE OLEFIN POLYMERIZATION CATALYST ACTIVATOR | THE DOW CHEMICAL COMPANY (US) | 1997-10-02 | — | — | WO | disclosed |
| WO-1997035892-A1 | SOLUTION POLYMERIZATION PROCESS WITH DISPERSED CATALYST ACTIVATOR | THE DOW CHEMICAL COMPANY (US) | 1997-10-02 | — | — | WO | disclosed |
| EP-0793679-A1 | ETHYLENE HOMOPOLYMERIZATION USING GROUP 3 METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1997-09-10 | — | — | EP | disclosed |
| EP-0781299-A2 | SILYLIUM CATIONIC POLYMERIZATION ACTIVATORS FOR METALLOCENE COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1997-07-02 | — | — | EP | disclosed |
| WO-1997019965-A1 | MONO-OLEFIN/POLYENE INTERPOLYMERS, METHOD OF PREPARATION, COMPOSITIONS CONTAINING THE SAME, AND ARTICLES MADE THEREOF | THE DOW CHEMICAL COMPANY (US) | 1997-06-05 | — | — | WO | disclosed |
| WO-1997019959-A1 | SUPPORTED CATALYST CONTAINING TETHERED CATION FORMING ACTIVATOR | THE DOW CHEMICAL COMPANY (US) | 1997-06-05 | — | — | WO | disclosed |
| US-5625087-A | Silylium cationic polymerization activators for metallocene complexes | THE DOW CHEMICAL COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| WO-1996016095-A1 | ETHYLENE HOMOPOLYMERIZATION USING GROUP 3 METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1996-05-30 | — | — | WO | disclosed |
| WO-1996008519-A2 | SILYLIUM CATIONIC POLYMERIZATION ACTIVATORS FOR METALLOCENE COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1996-03-21 | — | — | WO | disclosed |
| US-5464906-A | Polymerization catalyst | THE DOW CHEMICAL COMPANY (US) | 1995-11-07 | — | — | US | disclosed |