Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CDC25A | P30304 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.30 |
| ▸ | MAOA | P21397 | 3/20 | 0.30 |
| ▸ | MAOB | P27338 | 3/20 | 0.30 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27494195 | 0.86 | KCNQ2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL5144001 | 0.85 | BRD4 (0.32) | BRD4 | |
| SCHEMBL5859348 | 0.81 | CHRNB2 (0.33) | CHRNB2CHRNA4MEN1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL4467654 | 0.81 | MAPT (0.35) | NISCH | |
| Hydrochloric Acid SCHEMBL16394842 | 0.81 | RXRA (0.31) | — | |
| Hydrochloric Acid SCHEMBL27495446 | 0.81 | CHRNB2 (0.31) | CHRNB2CHRNA4MEN1POLBKMT2A | |
| SCHEMBL7853080 | 0.80 | CHRNB2 (0.32) | CHRNB2CHRNA4MEN1POLBKMT2A | |
| SCHEMBL27642869 | 0.80 | CHRNB2 (0.32) | CHRNB2CHRNA4MEN1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL2512974 | 0.80 | CYP2A6 (0.30) | — | |
| Hydrochloric Acid SCHEMBL2508930 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106632781-B | Process for producing ethylene/propylene copolymer having branched structure and the copolymer | 中国石油化工股份有限公司 | 2020-05-12 | — | — | CN | claimed |
| CN-114599661-B | Transition metal compound, method for preparing the same, and catalyst composition comprising the same | 株式会社LG化学 | 2024-03-12 | — | — | CN | disclosed |
| CN-114599661-A | Transition metal compound, method for preparing the same, and catalyst composition comprising the same | 株式会社LG化学 | 2022-06-07 | — | — | CN | disclosed |
| CN-106632781-B | Process for producing ethylene/propylene copolymer having branched structure and the copolymer | 中国石油化工股份有限公司 | 2020-05-12 | — | — | CN | disclosed |
| US-7342078-B2 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | BASELL POLYOLEFINE GMBH (DE) | 2008-03-11 | — | — | US | disclosed |
| EP-1119575-A1 | BRIDGED METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000020426-A1 | BRIDGED METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2000-04-13 | — | — | WO | disclosed |