Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27499523 | 0.78 | USP7 (0.42) | ADRA2CUSP7CNR1CNR2CLK4 | |
| SCHEMBL1982971 | 0.76 | CYP2A6 (0.43) | ADRA2CUSP7CLK4CTSSCTSK | |
| SCHEMBL5086336 | 0.76 | ADRA2C (0.44) | ADRA2CUSP7CNR1CNR2CLK4 | |
| SCHEMBL13266542 | 0.73 | GABRG2 (0.49) | ADRA2CCLK4CTSSCTSKGABRG2 | |
| SCHEMBL10244532 | 0.71 | CYP2A6 (0.57) | CLK4CTSSCTSKGABRG2GABRB3 | |
| SCHEMBL8982347 | 0.71 | CYP2A6 (0.57) | CLK4CTSSCTSKGABRG2GABRB3 | |
| SCHEMBL4429831 | 0.70 | CLK4 (0.41) | ADRA2CUSP7CLK4ENPP1PGR | |
| SCHEMBL1982974 | 0.70 | ADRA2C (0.50) | ADRA2CUSP7CNR1CNR2CLK4 | |
| SCHEMBL4429834 | 0.70 | ENPP1 (0.42) | ADRA2CCLK4ENPP1PGRLRRK2 | |
| SCHEMBL10980808 | 0.69 | ADRA2C (0.68) | ADRA2CUSP7CNR1CNR2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008091594-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |