SCHEMBL5086388

SCHEMBL5086388

C=CCOc1c(Br)cc(C)cc1C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.40
LMNA P02545 3/20 0.40
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2D6 P10635 2/20 0.36
HTT P42858 2/20 0.36
ALDH1A1 P00352 2/20 0.35
CYP2C19 P33261 2/20 0.35
CA2 P00918 1/20 0.35
POLB P06746 1/20 0.35
TYR P14679 1/20 0.35
CYP1A2 P05177 1/20 0.35
KDM4E B2RXH2 2/20 0.34
PKM P14618 1/20 0.34
HPGD P15428 1/20 0.34
GAA P10253 2/20 0.33
HSPA5 P11021 1/20 0.33
CYP2C9 P11712 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29605909 1.00 SMN1; SMN2 (0.40) SMN1; SMN2LMNAMEN1KMT2ACYP3A4
SCHEMBL9255038 0.89 CYP2D6 (0.43) SMN1; SMN2LMNAMEN1KMT2ACYP3A4
SCHEMBL6675529 0.86 CYP2D6 (0.40) SMN1; SMN2LMNAMEN1KMT2ACYP3A4
SCHEMBL6578128 0.85 LMNA (0.47) SMN1; SMN2LMNAMEN1KMT2ACYP3A4
SCHEMBL5086413 0.84 LMNA (0.40) SMN1; SMN2LMNAMEN1KMT2ACYP2D6
SCHEMBL30832649 0.83 CA1 (0.42) SMN1; SMN2LMNAMEN1KMT2ACYP3A4
SCHEMBL5090305 0.83 CA1 (0.42) SMN1; SMN2LMNAMEN1KMT2ACYP3A4
SCHEMBL5089894 0.83 LMNA (0.39) SMN1; SMN2LMNAMEN1KMT2AHTT
SCHEMBL5086988 0.80 MAPT (0.47) SMN1; SMN2LMNAMEN1KMT2ACYP3A4
SCHEMBL5086986 0.78 CYP2D6 (0.38) SMN1; SMN2LMNAMEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1185236-C Transition metal compound, its producing process olefine polymerization catalyst containing the same transition metal compound and process for producing olefine polymer SUMITOMO CHEMICAL CO (JP) 2005-01-19 CN claimed
US-12617880-B2 Compounds for use in catalyst compositions for the production of polyolefins SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2026-05-05 US disclosed
US-20240392044-A1 OLEFIN POLYMERIZATION CATALYST SYSTEM AND POLYMERIZATION PROCESS NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2024-11-28 US disclosed
EP-4405367-A1 OLEFIN POLYMERIZATION CATALYST SYSTEM AND POLYMERIZATION PROCESS Nova Chemicals (International) S.A. (CH) 2024-07-31 EP disclosed
CN-117980314-A Olefin polymerization catalyst system and polymerization process 诺瓦化学品(国际)股份有限公司 2024-05-03 CN disclosed
CN-114364707-B Compounds in catalyst compositions for the production of polyolefins SABIC环球技术有限责任公司 2023-09-19 CN disclosed
CN-111247157-B Novel transition metal compound, catalyst composition comprising the same, and method for preparing ethylene homopolymer or copolymer of ethylene and alpha-olefin using the same 沙特基础工业爱思开NEXLENE私人有限公司 2023-03-28 CN disclosed
WO-2023042155-A1 OLEFIN POLYMERIZATION CATALYST SYSTEM AND POLYMERIZATION PROCESS NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2023-03-23 WO disclosed
US-20220332861-A1 COMPOUNDS FOR USE IN CATALYST COMPOSITIONS FOR THE PRODUCTION OF POLYOLEFINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-10-20 US disclosed
EP-4028437-A1 COMPOUNDS FOR USE IN CATALYST COMPOSITIONS FOR THE PRODUCTION OF POLYOLEFINS SABIC Global Technologies, B.V. (NL) 2022-07-20 EP disclosed
CN-102666607-A Olefinic polymers SUMITOMO CHEMICAL CO 2012-09-12 CN disclosed
EP-1498178-B1 Transition metal complex and process for producing the same SUMITOMO CHEMICAL CO (JP) 2008-06-11 EP disclosed
EP-1498178-A2 Transition metal complex, process for producing the same, olefin polymerization catalyst containing the transition metal complex and process for producing olefin polymers Sumitomo Chemical Company, Limited (JP) 2005-01-19 EP disclosed
CN-1185236-C Transition metal compound, its producing process olefine polymerization catalyst containing the same transition metal compound and process for producing olefine polymer SUMITOMO CHEMICAL CO (JP) 2005-01-19 CN disclosed
EP-0842939-B1 OLEFIN POLYMERIZATION CATALYST CONTAINING A TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING OLEFIN POLYMERS SUMITOMO CHEMICAL CO (JP) 2004-10-06 EP disclosed
US-6329478-B1 SOLUBILITY IN SATURATED HYDROCARBON SOLVENTS SUMITMO CHEMICAL COMPANY, LIMITED 2001-12-11 US disclosed
CN-1310183-A Transition metal compound, its producing process olefine polymerization catalyst containing the same transition metal compound and process for producing olefine polymer SUMITOMO CHEMICAL CO (JP) 2001-08-29 CN disclosed
CN-1068884-C Transition metal complex, process for producing the same, olefin polymerization catalyst containing the transition metal complex, and process for producing olefin polymer SUMITOMO CHEM IND (JP) 2001-07-25 CN disclosed
CN-1193323-A Transition metal complex, process for producing the same, olefin polymerization catalyst containing the transition metal complex, and process for producing olefin polymer SUMITOMO CHEM IND (JP) 1998-09-16 CN disclosed
EP-0842939-A1 TRANSITION METAL COMPLEX, PROCESS FOR THE PREPARATION THEREOF, POLYMERIZATION CATALYST FOR OLEFINS CONTAINING THE COMPLEX, AND PROCESS FOR PRODUCING OLEFIN POLYMERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-05-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617880-B2 Compounds for use in catalyst compositions for the production of polyolefins PRMT5, CBR3, MET SMN1; SMN2 3764/4885LMNA 3822/4885MEN1 783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.