Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1406485 | 0.89 | KDM4E (0.47) | MEN1KMT2AKDM4EMAPTGAA | |
| SCHEMBL1406230 | 0.81 | MAPT (0.54) | MEN1KMT2ATDP1KDM4EMAPT | |
| SCHEMBL1406253 | 0.74 | SLC16A3 (0.59) | MEN1KMT2ATDP1KDM4EMAPT | |
| SCHEMBL19184746 | 0.73 | KDM4E (0.51) | MEN1KMT2ATDP1KDM4EMAPT | |
| SCHEMBL1406630 | 0.72 | ALDH1A1 (0.71) | MEN1KMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL19871176 | 0.70 | CA12 (0.44) | MEN1KMT2AKDM4EMAPTGAA | |
| SCHEMBL14326164 | 0.70 | MAOB (0.65) | KMT2AKDM4EMAPTGAAALDH1A1 | |
| SCHEMBL1406487 | 0.70 | NPC1 (0.56) | MEN1KMT2AKDM4EMAPTGAA | |
| SCHEMBL6687156 | 0.66 | ALDH1A1 (0.77) | MEN1KMT2ATDP1KDM4EMAPT | |
| SCHEMBL6503060 | 0.66 | NAPRT (0.52) | MEN1KMT2AKDM4EGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008013928-A2 | TREATMENT OF CANCER WITH INTERFERON GENE DELIVERY IN COMBINATION WITH A TGF-BETA INHIBITOR | BIOGEN IDEC MA INC. (US) | 2008-01-31 | — | — | WO | disclosed |