Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 19/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 16/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL871941 | 0.95 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2TP53CYP3A4 | |
| SCHEMBL8606048 | 0.95 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2TP53CYP3A4 | |
| SCHEMBL8040636 | 0.95 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL5313076 | 0.94 | SLC6A3 (0.51) | SLC6A3SLC6A4SLC6A2TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL10761073 | 0.93 | SLC6A3 (0.50) | SLC6A3SLC6A4SLC6A2TP53CYP3A4 | |
| SCHEMBL15065548 | 0.92 | SLC6A3 (0.47) | SLC6A3SLC6A4SLC6A2TP53CYP3A4 | |
| SCHEMBL5085857 | 0.88 | SLC6A3 (0.63) | SLC6A3SLC6A4SLC6A2TP53CYP3A4 | |
| SCHEMBL15065680 | 0.87 | LMNA (0.42) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL15065354 | 0.85 | LMNA (0.43) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL5141685 | 0.85 | SLC6A3 (0.62) | SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797870-A1 | COMPOSITIONS, SYNTHESIS, AND METHODS OF USING PHENYLCYCLOALKYLMETHYLAMINE DERIVATIVES | Reviva Pharmaceuticals, Inc. (US) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013102195-A1 | COMPOSITIONS, SYNTHESIS, AND METHODS OF USING PHENYLCYCLOALKYLMETHYLAMINE DERIVATIVES | REVIVA PHARMACEUTICALS, INC. (US) | 2013-07-04 | — | — | WO | disclosed |
| EP-1976513-A2 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | Sepracor, Inc. (US) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007081857-A2 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | SEPRACOR INC. (US) | 2007-07-19 | — | — | WO | disclosed |