Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 19/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 18/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL872307 | 0.96 | SLC6A3 (0.61) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL5086480 | 0.85 | SLC6A3 (0.59) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL5086379 | 0.84 | SLC6A3 (0.63) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL5087133 | 0.84 | SLC6A3 (0.63) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL8606048 | 0.80 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL871941 | 0.80 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL8040636 | 0.80 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL15065680 | 0.80 | LMNA (0.42) | SLC6A3SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL5433219 | 0.79 | SLC6A3 (0.60) | SLC6A3SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL5313076 | 0.79 | SLC6A3 (0.51) | SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101394847-B | Cycloalkylamines as monoamine reuptake inhibitors | 塞普拉柯公司 | 2017-05-24 | — | — | CN | claimed |
| EP-1976513-A2 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | Sepracor, Inc. (US) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007081857-A2 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | SEPRACOR INC. (US) | 2007-07-19 | — | — | WO | disclosed |