SCHEMBL50865

SCHEMBL50865

O=C1C=CCc2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.50
MAOB P27338 3/20 0.50
CDC25B P30305 2/20 0.50
IDO1 P14902 2/20 0.50
AKT1 P31749 1/20 0.50
SNCA P37840 1/20 0.50
MAP2K1 Q02750 1/20 0.50
PIN1 Q13526 1/20 0.50
EHMT2 Q96KQ7 1/20 0.50
NSD1 Q96L73 1/20 0.50
EHMT1 Q9H9B1 1/20 0.50
CES1 P23141 4/20 0.43
BCHE P06276 3/20 0.40
KMT2A Q03164 4/20 0.39
ACHE P22303 3/20 0.39
CA12 O43570 1/20 0.39
CA9 Q16790 1/20 0.39
CYP2A6 P11509 1/20 0.39
CYP1A2 P05177 1/20 0.37
TDP2 O95551 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30252635 1.00 MAOA (0.50) MAOAMAOBCDC25BIDO1AKT1
Hydrochloric Acid SCHEMBL30537100 0.98 MAOA (0.48) MAOAMAOBCDC25BIDO1AKT1
Hydrochloric Acid SCHEMBL2710069 0.98 MAOA (0.48) MAOAMAOBCDC25BIDO1AKT1
Bicarbonate SCHEMBL4535593 0.92 MAOA (0.43) MAOAMAOBCDC25BIDO1AKT1
Acetic Acid SCHEMBL7042249 0.89 MAOA (0.40) MAOAMAOBCDC25BIDO1AKT1
Hydrochlorthiazide SCHEMBL6010085 0.80 CDC25B (0.33) MAOAMAOBCDC25BIDO1AKT1
SCHEMBL30252240 0.78 CES1 (0.50) MAOAMAOBCDC25BIDO1AKT1
SCHEMBL11337168 0.78 CES1 (0.50) MAOAMAOBCDC25BIDO1AKT1
SCHEMBL20366857 0.77 CDC25B (0.56) MAOAMAOBCDC25BIDO1AKT1
SCHEMBL57446 0.76 MAOA (0.46) MAOAMAOBCDC25BIDO1AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2124 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121248445-B Naphthalene type chalcone compound and preparation method and application thereof BOZHOU UNIVERSITY (CN) 2026-05-26 CN claimed
CN-117659690-B Nylon 66 composite material and preparation method and application thereof 江苏金发科技新材料有限公司 2025-04-25 CN claimed
CN-119708718-A Preparation method of blue light diffusion prevention product of polymer material 志源塑胶制品(惠州)有限公司 2025-03-28 CN claimed
CN-118271276-B Naphthalenone derivative for promoting wound healing as well as preparation method and application thereof 广州市朝利良生物科技有限公司 2024-08-23 CN claimed
CN-114479409-B High-temperature-resistant injection-resistant retention-coloring polycarbonate composite material and preparation method and application thereof 江苏金发科技新材料有限公司 2024-08-06 CN claimed
CN-118339694-A Nonaqueous electrolyte composition and lithium secondary battery comprising same 株式会社LG新能源 2024-07-12 CN claimed
CN-118108924-B Halogen-free flame-retardant polyurethane elastomer and preparation process thereof 上海皆利新材料科技有限公司 2024-07-02 CN claimed
CN-118271276-A Naphthalenone derivative for promoting wound healing as well as preparation method and application thereof 广州市朝利良生物科技有限公司 2024-07-02 CN claimed
CN-118206419-A Conjugated diene dimer, aerospace fuel and preparation method thereof 天津大学 2024-06-18 CN claimed
CN-118146061-A Method for photo-catalytic isomerization of cis-1, 3-diene 武汉光化学技术研究院 2024-06-07 CN claimed
EP-0291327-A2 Aryl-substituted naphthalene, benzoxepine, benzazepine and benzocycloheptene derivatives SCHERING CORPORATION (US) 1988-11-17 EP claimed
EP-0204952-B1 PROCESS FOR THE PRODUCTION OF 4,4,7-TRIMETHYL-3,4,7,8,-TETRAHYDRO-2 (6H)-NAPHTHALENONE, PURE OR MIXED WITH 3,5,5-TRIMETHYL-4-BUTENYLIDENE-CYCLOHEX-2-EN-1-ONES, PRODUCTS OBTAINED FROM THESE AND THEIR USES AS PERFUMES AND AROMAS Dragoco Gerberding & Co. GmbH (DE) 1988-09-28 EP claimed
US-4753924-A ORGANOLEPTIC DRAGOCO GERBERDING & CO. GMBH (DE) 1988-06-28 US claimed
EP-0244167-A1 Improved process for preparing poly (aryl ethers) and poly (aryl ether ketones) AMOCO CORPORATION (US) 1987-11-04 EP claimed
US-4671798-A DIELS-ALDER, REDUCTION; COSMETICS, DETERGENTS, SHAMPOO FIRMENICH SA (CH) 1987-06-09 US claimed
EP-0102833-B1 CARBOXYLATION OF METAL ARYLOXIDES Euroceltique S.A. (LU) 1986-08-13 EP claimed
US-4593129-A Polyphosphazene process ETHYL CORPORATION (US) 1986-06-03 US claimed
EP-0102833-A1 Carboxylation of metal aryloxides Euroceltique S.A. (LU) 1984-03-14 EP claimed
US-4418087-A Mixture of 4,4A,5,6-tetrahydro-7-methyl-2-(3H)-naphthalenone and benzodioxanones and use thereof in augmenting or enhancing the aroma or taste of consumable materials INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1983-11-29 US claimed
US-4201800-A Hardened photoresist master image mask process INTERNATIONAL BUSINESS MACHINES CORP. (US) 1980-05-06 US claimed