Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Butadiene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butadiene SCHEMBL37186 | 1.00 | — | — | |
| Butadiene SCHEMBL28233035 | 0.95 | — | — | |
| Butadiene SCHEMBL28898214 | 0.95 | LMNA (0.50) | LMNACA1CA2CA9TSHR | |
| Butadiene SCHEMBL3066828 | 0.95 | — | — | |
| Butadiene SCHEMBL28174422 | 0.88 | LMNA (0.44) | LMNACA1CA2CA9TSHR | |
| Butadiene SCHEMBL29085600 | 0.88 | LMNA (0.44) | LMNACA1CA2CA9TSHR | |
| Oxalic Acid SCHEMBL17985765 | 0.86 | LMNA (0.50) | LMNACA1CA2CA9TSHR | |
| Butadiene SCHEMBL11197818 | 0.84 | — | — | |
| Acrylic Acid SCHEMBL5971713 | 0.82 | LMNA (0.83) | LMNACA1CA2CA9TSHR | |
| Butadiene SCHEMBL10491798 | 0.82 | LMNA (0.47) | LMNACA1CA2CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025083313-A1 | METHOD FOR PRODUCING CYCLIC CARBONATES FROM CO2 BY USING MXENES AS CATALYSTS | UNIVERSITAT POLITÈCNICA DE VALÈNCIA (ES) | 2025-04-24 | — | — | WO | disclosed |
| EP-2990112-B1 | METHOD FOR MANUFACTURING CATALYST FOR SYNTHESIZING CYCLIC CARBONATE | MARUZEN PETROCHEM CO LTD (JP) | 2020-03-25 | — | — | EP | disclosed |
| EP-2990113-B1 | METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS | MARUZEN PETROCHEM CO LTD (JP) | 2020-03-25 | — | — | EP | disclosed |
| EP-3150588-B1 | APPARATUS AND METHOD FOR PRODUCING CYCLIC CARBONATE | MARUZEN PETROCHEM CO LTD (JP) | 2019-07-03 | — | — | EP | disclosed |
| US-10106520-B2 | Apparatus and method for producing cyclic carbonate | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2018-10-23 | — | — | US | disclosed |
| US-10029241-B2 | Method for producing catalyst for cyclic carbonate synthesis | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2018-07-24 | — | — | US | disclosed |
| EP-3023418-B1 | METHOD FOR MANUFACTURING CYCLIC CARBONATE | AIST (JP) | 2018-07-11 | — | — | EP | disclosed |
| US-10011621-B2 | Method for producing silica gel-immobolized phosphonium salt catalysts | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2018-07-03 | — | — | US | disclosed |
| EP-3023419-B1 | METHOD FOR CONTINUOUSLY PRODUCING CYCLIC CARBONATE | MARUZEN PETROCHEM CO LTD (JP) | 2018-01-31 | — | — | EP | disclosed |
| US-9856229-B2 | Method for producing cyclic carbonate | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2018-01-02 | — | — | US | disclosed |
| EP-3023419-A1 | METHOD FOR CONTINUOUSLY PRODUCING CYCLIC CARBONATE | Maruzen Petrochemical Co., Ltd. (JP) | 2016-05-25 | — | — | EP | disclosed |
| EP-3018163-A1 | Novel polyurethanes free from isocyanate groups | BASF SE (DE) | 2016-05-11 | — | — | EP | disclosed |
| US-20160108071-A1 | METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2016-04-21 | — | — | US | disclosed |
| US-20160067695-A1 | METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2016-03-10 | — | — | US | disclosed |
| US-20160060242-A1 | METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2016-03-03 | — | — | US | disclosed |
| EP-2990114-A1 | METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS | National Institute of Advanced Industrial Science and Technology (JP) | 2016-03-02 | — | — | EP | disclosed |
| EP-2990113-A1 | METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS | Maruzen Petrochemical Co., Ltd. (JP) | 2016-03-02 | — | — | EP | disclosed |
| EP-2990112-A1 | METHOD FOR MANUFACTURING CATALYST FOR SYNTHESIZING CYCLIC CARBONATE | Maruzen Petrochemical Co., Ltd. (JP) | 2016-03-02 | — | — | EP | disclosed |
| WO-2015160773-A1 | ELECTROLYTE FORMULATIONS | WILDCAT DISCOVERY TECHNOLOGIES INC. (US) | 2015-10-22 | — | — | WO | disclosed |
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160067695-A1 | METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS | CYCS, CA7, CA9 | LMNA 3426/4885CA1 15/4885CA2 10/4885 |
| US-10029241-B2 | Method for producing catalyst for cyclic carbonate synthesis | CYCS, CA7, CA9 | LMNA 3426/4885CA1 15/4885CA2 10/4885 |
| US-20160108071-A1 | METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS | EPHX2, CA4, CA9 | LMNA 1304/4885CA1 79/4885CA2 11/4885 |
| US-10106520-B2 | Apparatus and method for producing cyclic carbonate | SCO2, CA2, AGL | LMNA 3569/4885CA1 4/4885CA2 2/4885 |
| US-20160060242-A1 | METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS | CA2, PLCB3, PHOSPHO1 | LMNA 1548/4885CA1 28/4885CA2 1/4885 |
| US-10011621-B2 | Method for producing silica gel-immobolized phosphonium salt catalysts | SIK2, SIK3, SIK1 | LMNA 1871/4885CA1 148/4885CA2 87/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.