Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | IDO1 | P14902 | 2/20 | 0.64 |
| ▸ | APP | P05067 | 16/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3500426 | 0.90 | TSHR (0.71) | CYP3A4IDO1APPTSHR | |
| SCHEMBL668783 | 0.88 | APP (0.68) | CYP3A4IDO1APPTSHR | |
| SCHEMBL20004451 | 0.86 | CYP3A4 (0.50) | CYP3A4IDO1APPTSHRHRH4 | |
| SCHEMBL3165593 | 0.85 | CYP3A4 (0.54) | CYP3A4IDO1APPHRH4HRH3 | |
| SCHEMBL745219 | 0.85 | CYP3A4 (0.54) | CYP3A4IDO1APPHRH4HRH3 | |
| SCHEMBL20158188 | 0.83 | CYP3A4 (0.52) | CYP3A4IDO1APPHRH4HRH3 | |
| SCHEMBL6406620 | 0.81 | CYP3A4 (0.50) | CYP3A4IDO1APPHRH4HRH3 | |
| SCHEMBL21306509 | 0.81 | CYP3A4 (0.50) | CYP3A4IDO1APPHRH4HRH3 | |
| SCHEMBL17758157 | 0.79 | CYP3A4 (0.48) | CYP3A4IDO1APPHRH4HRH3 | |
| SCHEMBL17518179 | 0.79 | APP (0.49) | CYP3A4IDO1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2545085-B1 | Radiopaque, non-biodegradable, water-insoluble iodinated benzyl ethers of poly(vinyl alcohol), preparation method thereof, injectable embolizing compositions containing thereof and use thereof | UNIVERSITÉ CLAUDE BERNARD LYON 1 UCBL (FR) | 2016-10-19 | — | — | EP | disclosed |
| US-9434800-B2 | Method of embolization using a radiopaque, non-biodegradable, water-insoluble iodinated benzyl ether of polyl(vinyl alcohol) | ANTIA THERAPEUTICS S.A. (CH) | 2016-09-06 | — | — | US | disclosed |
| US-9198913-B2 | Nitroimidazooxazines and their uses in anti-tubercular therapy | GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT (US) | 2015-12-01 | — | — | US | disclosed |
| US-20150335779-A1 | Method of Embolization using a Radiopaque, Non-Biodegradable, Water-Insoluble Iodinated Benzyl Ether of PolyI(Vinyl Alcohol) | ANTIA THERAPEUTICS S.A. (CH) | 2015-11-26 | — | — | US | disclosed |
| US-9115230-B2 | Radiopaque, non-biodegradable, water-insoluble iodinated benzyl ethers of poly(vinyl alcohol), preparation method thereof, injectable embolizing compositions containing thereof and use thereof | ANTIA THERAPEUTICS S.A. (CH) | 2015-08-25 | — | — | US | disclosed |
| EP-2459571-B1 | NITROIMIDAZOOXAZINES AND THEIR USES IN ANTI-TUBERCULAR THERAPY | GLOBAL ALLIANCE FOR TB DRUG DEV (US) | 2015-03-11 | — | — | EP | disclosed |
| US-20130108574-A1 | RADIOPAQUE, NON-BIODEGRADABLE, WATER-INSOLUBLE IODINATED BENZYL ETHERS OF POLY(VINYL ALCOHOL), PREPARATION METHOD THEREOF, INJECTABLE EMBOLIZING COMPOSITIONS CONTAINING THEREOF AND USE THEREOF | MERIT MEDICAL SYSTEMS, INC. | 2013-05-02 | — | — | US | disclosed |
| EP-2545085-A1 | RADIOPAQUE, NON- BIODEGRADABLE, WATER - INSOLUBLE IODINATED BENZYL ETHERS OF POLY (VINYL ALCOHOL), PREPARATION METHOD THEREOF, INJECTABLE EMBOLIZING COMPOSITIONS CONTAINING THEREOF AND USE THEREOF | Universite Claude Bernard Lyon 1 (UCBL) (FR) | 2013-01-16 | — | — | EP | disclosed |
| EP-2459571-A1 | NITROIMIDAZOOXAZINES AND THEIR USES IN ANTI-TUBERCULAR THERAPY | Global Alliance For Tb Drug Development (US) | 2012-06-06 | — | — | EP | disclosed |
| US-20120028973-A1 | NITROIMIDAZOOXAZINES AND THEIR USES IN ANTI-TUBERCULAR THERAPY | GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT (US) | 2012-02-02 | — | — | US | disclosed |
| WO-2003082301-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | THRESHOLD PHARMACEUTICALS, INC. (US) | 2003-10-09 | — | — | WO | disclosed |
| US-6172117-B1 | APPLYING THIOCYANATOALKYL QUATERNARY AMMONIUM SALTS TO WOOD | AKZO NOBEL N.V. (NL) | 2001-01-09 | — | — | US | disclosed |
| EP-0918811-B1 | POLY(ARYLAMINES) AND FILMS THEREOF | DOW CHEMICAL CO (US) | 2000-12-27 | — | — | EP | disclosed |
| US-5948552-A | Heat-resistant organic electroluminescent device | HEWLETT-PACKARD COMPANY (US) | 1999-09-07 | — | — | US | disclosed |
| WO-1999043212-A2 | WOOD PRESERVATIVES | AKZO NOBEL N.V. (NL) | 1999-09-02 | — | — | WO | disclosed |
| US-5929194-A | POLY(TERT-DI OR POLYARYLAMINE) CONTAINING END GROUPS, IN EACH OCCURANCE SELECTED BY HYDROXY, GLYCIDYL ETHER, ACRYLATE OR METHACRYLATES, ETHENYL, ETHYNYL, VINYLBENZOXY, IMIDES, TRIFLUROVINYL ETHER AND BOUNDED CYCLOBUTENE | THE DOW CHEMICAL COMPANY (US) | 1999-07-27 | — | — | US | disclosed |
| EP-0918811-A1 | POLY(ARYLAMINES) AND FILMS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1999-06-02 | — | — | EP | disclosed |
| US-5728801-A | FILMS USEFUL AS CHARGE TRANSPORT LAYERS IN LIGHT-EMITTING DIODES | THE DOW CHEMICAL COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| EP-0827366-A2 | Heat-resistant organic electroluminescent device | Hewlett-Packard Company (US) | 1998-03-04 | — | — | EP | disclosed |
| WO-1998006773-A1 | POLY(ARYLAMINES) AND FILMS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028973-A1 | NITROIMIDAZOOXAZINES AND THEIR USES IN ANTI-TUBERCULAR THERAPY | NOX5, MT-ND5, NQO1 | CYP3A4 930/4885IDO1 220/4885APP 4663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.