Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL868015 | 0.97 | ALDH1A1 (0.42) | ALDH1A1TDP1CA2CA1FDPS | |
| Water SCHEMBL3620213 | 0.95 | ALDH1A1 (0.41) | ALDH1A1TDP1CA2CA1FDPS | |
| Hydrochloric Acid SCHEMBL5087173 | 0.95 | ALDH1A1 (0.41) | ALDH1A1TDP1CA2CA1FDPS | |
| Bromide SCHEMBL524276 | 0.95 | ALDH1A1 (0.41) | ALDH1A1TDP1CA2CA1FDPS | |
| Iodide SCHEMBL5088501 | 0.93 | OPRM1 (0.42) | ALDH1A1TDP1FDPSDNM1TSHR | |
| Iodide SCHEMBL5088373 | 0.91 | FDPS (0.42) | FDPSDNM1TSHRCYP3A4OPRM1 | |
| Iodide SCHEMBL5091402 | 0.91 | FDPS (0.42) | FDPSDNM1TSHRCYP3A4OPRM1 | |
| Iodide SCHEMBL5087651 | 0.91 | FDPS (0.42) | FDPSDNM1TSHRCYP3A4OPRM1 | |
| Iodide SCHEMBL5091780 | 0.91 | FDPS (0.42) | FDPSDNM1TSHRCYP3A4OPRM1 | |
| Iodide SCHEMBL5086849 | 0.91 | FDPS (0.42) | FDPSDNM1TSHRCYP3A4OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4166712-A1 | METHOD FOR PRODUCING COAGULATED MATERIAL | DIC Corporation (JP) | 2023-04-19 | — | — | EP | disclosed |
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |