Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.81 |
| ▸ | TP53 | P04637 | 1/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.81 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.81 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.81 |
| ▸ | SLC22A1 | O15245 | 4/20 | 0.80 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.80 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5087865 | 1.00 | ALDH1A1 (0.81) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL3105057 | 1.00 | ALDH1A1 (0.81) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5091866 | 0.97 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5085129 | 0.97 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5087895 | 0.97 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5091659 | 0.97 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL3087580 | 0.97 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL892744 | 0.97 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL3094792 | 0.97 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5087153 | 0.97 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065601-A | Two phase electrolytes used as halogen traps in metal halogen secondary cells and batteries | ECO-CONTROL, INC. (US) | 1977-12-27 | — | — | US | claimed |
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |
| EP-0004606-B1 | PROCESS FOR PREPARING ANILINE COMPOUNDS | ETHYL CORPORATION (US) | 1982-03-10 | — | — | EP | disclosed |
| US-4186147-A | DISPLACEMENT OF THIOCYANOANILINE WITH AN ALCOHOL TO FORM THIOALKYL ANILINE | ETHYL CORPORATION (US) | 1980-01-29 | — | — | US | disclosed |
| US-4022816-A | TRIALKYL AMMONIUM OR PHOSPHONIUM CATALYST | ETHYL CORPORATION (US) | 1977-05-10 | — | — | US | disclosed |