Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL11120034 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1LMNATP53DNM1 | |
| Iodide SCHEMBL2385633 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1LMNATP53DNM1 | |
| Iodide SCHEMBL1502936 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1LMNATP53DNM1 | |
| Iodide SCHEMBL10486489 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1LMNATP53DNM1 | |
| Iodide SCHEMBL5137819 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1LMNATP53DNM1 | |
| Iodide SCHEMBL23275376 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1LMNATP53DNM1 | |
| Iodide SCHEMBL5092090 | 1.00 | OPRM1 (0.46) | OPRM1SPHK1LMNATP53DNM1 | |
| Iodide SCHEMBL28233718 | 0.98 | OPRM1 (0.44) | OPRM1SPHK1LMNATP53DNM1 | |
| SCHEMBL37786 | 0.98 | OPRM1 (0.48) | OPRM1SPHK1LMNATP53DNM1 | |
| SCHEMBL17257510 | 0.98 | OPRM1 (0.48) | OPRM1SPHK1LMNATP53DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141689-A1 | LONG-LASTING ANTIMICROBIAL COMPOSITIONS CONTAINING CATIONIC ACTIVE AGENTS AND ANIONIC EXCIPIENTS AND USES | UNIVERSIDADE FEDERAL DE MINAS GERAIS - UFMG (BR) | 2023-08-03 | — | — | WO | disclosed |
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |