Azobenzene

Azobenzene

SCHEMBL508709

C=CC(=O)O.C=CC(=O)O.N#Cc1ccccc1-c1ccccc1.c1ccc(/N=N/c2ccccc2)cc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.47
MAOB P27338 4/20 0.45
MAOA P21397 3/20 0.45
PTPN5 P54829 1/20 0.42
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
FFAR1 O14842 1/20 0.40
AKR1B1 P15121 1/20 0.40
GABRG2 P18507 1/20 0.40
GABRB3 P28472 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40
GRIA2 P42262 1/20 0.39
GRIA4 P48058 1/20 0.39
MME P08473 1/20 0.38
RPS6KA3 P51812 1/20 0.38
KDM4E B2RXH2 1/20 0.38
GALR3 O60755 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL211815 0.91 ESR2 (0.56) ESR2PTPN5FFAR1AKR1B1GABRG2
Acrylic Acid SCHEMBL508710 0.89 ESR2 (0.40) ESR2MAOBMAOAPTPN5CASP3
Benzoic Acid SCHEMBL5166939 0.84 ESR2 (0.49) ESR2PTPN5FFAR1AKR1B1GRIA2
Azobenzene SCHEMBL27865838 0.78 ALDH1A1 (0.57) CASP3SENP8SENP7SENP6KDM4E
Azobenzene SCHEMBL30414107 0.78 ALDH1A1 (0.57) CASP3SENP8SENP7SENP6KDM4E
Azobenzene SCHEMBL509328 0.78 ALDH1A1 (0.57) CASP3SENP8SENP7SENP6KDM4E
Ethylene SCHEMBL28042734 0.76 ESR2 (0.64) ESR2MAOBMAOAPTPN5FFAR1
SCHEMBL29662886 0.76 ESR2 (0.69) ESR2MAOBMAOAPTPN5FFAR1
SCHEMBL223 0.76 ESR2 (0.69) ESR2MAOBMAOAPTPN5FFAR1
Water SCHEMBL3178714 0.76 ESR2 (0.69) ESR2MAOBMAOAPTPN5FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8435333-B2 Photo-switchable membrane and method UNIVERSITY OF ROCHESTER (US) 2013-05-07 US disclosed
US-20120025136-A1 PHOTO-SWITCHABLE MEMBRANE AND METHOD UNIVERSITY OF ROCHESTER (US) 2012-02-02 US disclosed