Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8286618 | 0.83 | CA12 (0.37) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL398615 | 0.83 | GABBR2 (0.47) | METAP1CYP1A2CYP3A4 | |
| SCHEMBL5093197 | 0.83 | CA12 (0.37) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL5509358 | 0.78 | CA12 (0.39) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL5085515 | 0.76 | ADH1B (0.38) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL10901126 | 0.76 | LMNA (0.43) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL2951190 | 0.73 | METAP1 (0.49) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL5379957 | 0.73 | METAP1 (0.41) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL6361016 | 0.72 | GABBR2 (0.52) | CYP1A2CYP3A4 | |
| SCHEMBL2331815 | 0.72 | METAP1 (0.50) | CA12CA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033572-A1 | ACYLOXYALKYL CARBAMATE PRODRUGS, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2008-03-20 | — | — | WO | disclosed |