Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509196 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2MAPK1ATMLMNAHTT | |
| SCHEMBL7288407 | 0.83 | ACACB (0.32) | ACACB | |
| SCHEMBL2184592 | 0.83 | ACACB (0.32) | ACACB | |
| SCHEMBL2425411 | 0.83 | CTSS (0.36) | ATMMAPTNPSR1 | |
| SCHEMBL7400373 | 0.83 | CTSS (0.36) | ATMMAPTNPSR1 | |
| SCHEMBL8359365 | 0.82 | CTRB1 (0.46) | ATM | |
| SCHEMBL6218674 | 0.82 | CTRB1 (0.46) | ATM | |
| SCHEMBL3862108 | 0.80 | ITGB3 (0.40) | SMN1; SMN2MAPK1ATMLMNAHTT | |
| SCHEMBL3862102 | 0.80 | ITGB3 (0.40) | SMN1; SMN2MAPK1ATMLMNAHTT | |
| SCHEMBL9012656 | 0.79 | CTRB1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1266013-B1 | HEPARINASE III AND USES THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2014-10-15 | — | — | EP | disclosed |
| US-8748193-B2 | Apparatus for desorption and ionization of analytes | BAYLOR COLLEGE OF MEDICINE (US) | 2014-06-10 | — | — | US | disclosed |
| US-20120027744-A1 | MODIFIED HEPARINASE III AND METHODS OF SEQUENCING THEREWITH | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-02-02 | — | — | US | disclosed |
| US-7939292-B2 | Modified heparinase III and methods of sequencing therewith | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-05-10 | — | — | US | disclosed |
| US-20090256069-A1 | APPARATUS FOR DESORPTION AND IONIZATION OF ANALYTES | BAYLOR COLLEGE OF MEDICINE (US) | 2009-10-15 | — | — | US | disclosed |
| US-20090081635-A1 | MODIFIED HEPARINASE III AND METHODS OF SEQUENCING THEREWITH | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-03-26 | — | — | US | disclosed |
| US-7491549-B2 | Apparatus for desorption and ionization of analytes | BAYLOR COLLEGE OF MEDICINE (US) | 2009-02-17 | — | — | US | disclosed |
| US-7455986-B2 | Heparinase III and methods of specifically cleaving therewith | MASSACHUSETTS INSTITUTE OF TECHNOLOGY, INC. (US) | 2008-11-25 | — | — | US | disclosed |
| US-7413909-B2 | Method and apparatus for desorption and ionization of analytes | BAYLOR COLLEGE OF MEDICINE (US) | 2008-08-19 | — | — | US | disclosed |
| US-7390633-B2 | Methods for preparing low molecular weight heparin with modified heparinase III | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-06-24 | — | — | US | disclosed |
| EP-1266013-A2 | HEPARINASE III AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-12-18 | — | — | EP | disclosed |
| US-20020122793-A1 | Heparinase III and uses thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-09-05 | — | — | US | disclosed |
| US-20020037517-A1 | Methods for sequencing biopolymers | HUTCHENS WILLIAM T (US) | 2002-03-28 | — | — | US | disclosed |
| WO-2001066772-A2 | HEPARINASE III AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2001-09-13 | — | — | WO | disclosed |
| US-6124137-A | APPARATUS FOR DETECTING AN ANALYTE IMMOBILIZED TO A SURFACE; FOR RECEPTIVITY DIRECTED DETECTION OF BIOPLOYMERS; FOR SEQUENCING BIOPOLYMERS | BAYLOR COLLEGE OF MEDICINE (US) | 2000-09-26 | — | — | US | disclosed |
| US-6020208-A | Systems for surface-enhanced affinity capture for desorption and detection of analytes | BAYLOR COLLEGE OF MEDICINE (US) | 2000-02-01 | — | — | US | disclosed |
| US-5719060-A | Method and apparatus for desorption and ionization of analytes | BAYLOR COLLEGE OF MEDICINE (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0700521-A4 | METHOD AND APPARATUS FOR DESORPTION AND IONIZATION OF ANALYTES | BAYLOR COLLEGE MEDICINE (US) | 1997-06-11 | — | — | EP | disclosed |
| EP-0700521-A1 | METHOD AND APPARATUS FOR DESORPTION AND IONIZATION OF ANALYTES | BAYLOR COLLEGE OF MEDICINE (US) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994028418-A1 | METHOD AND APPARATUS FOR DESORPTION AND IONIZATION OF ANALYTES | BAYLOR COLLEGE OF MEDICINE (US) | 1994-12-08 | — | — | WO | disclosed |