Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 4/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1536830 | 1.00 | THRB (0.37) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL528801 | 1.00 | THRB (0.37) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL11792087 | 1.00 | THRB (0.37) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL1536941 | 1.00 | THRB (0.37) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL1516375 | 1.00 | THRB (0.37) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL534358 | 1.00 | THRB (0.37) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL1536946 | 1.00 | THRB (0.37) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL1537075 | 1.00 | THRB (0.37) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL535075 | 1.00 | THRB (0.37) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL1536821 | 1.00 | THRB (0.37) | THRBALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831305-B1 | GRAFT COPOLYMERS WITH SEGMENTED ARMS | COATINGS FOREIGN IP CO LLC (US) | 2015-08-12 | — | — | EP | disclosed |
| US-7402624-B2 | Graft copolymers with segmented arms and their preparation and use | E.I. DU PONT DE NEMOURS & COMPANY (US) | 2008-07-22 | — | — | US | disclosed |
| EP-1831305-A2 | GRAFT COPOLYMERS WITH SEGMENTED ARMS AND THEIR PREPARATION AND USE | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006052981-A2 | GRAFT COPOLYMERS WITH SEGMENTED ARMS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-05-18 | — | — | WO | disclosed |
| US-20060100305-A1 | Graft copolymers with segmented arms and their preparation and use | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2006-05-11 | — | — | US | disclosed |