SCHEMBL534358

SCHEMBL534358

C=CC(=O)OC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.37
ALDH1A1 P00352 4/20 0.31
TP53 P04637 3/20 0.31
HIF1A Q16665 3/20 0.31
CYP3A4 P08684 2/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TSHR P16473 4/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1536830 1.00 THRB (0.37) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL528801 1.00 THRB (0.37) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL11792087 1.00 THRB (0.37) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL1536941 1.00 THRB (0.37) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL1516375 1.00 THRB (0.37) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL1536946 1.00 THRB (0.37) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL1537075 1.00 THRB (0.37) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL535075 1.00 THRB (0.37) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL1536821 1.00 THRB (0.37) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL5087400 1.00 THRB (0.37) THRBALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122091709-A Composite solid electrolyte, preparation method thereof and secondary battery containing composite solid electrolyte 2026-05-26 CN claimed
US-12528966-B2 Coatings P2I LTD (GB) 2026-01-20 US claimed
CN-119954695-A Modifier and modified KNO3Powder, and preparation method and application thereof 国网江苏省电力有限公司超高压分公司 2025-05-09 CN claimed
EP-3307835-B2 COATINGS P2I LTD (GB) 2025-04-02 EP claimed
WO-2024259629-A1 MODIFIED CURRENT COLLECTOR FOR SECONDARY BATTERY GUANGDONG HAOZHI TECHNOLOGY CO. LIMITED (CN) 2024-12-26 WO claimed
CN-118738213-A Preparation method of paper-based perovskite X-ray detector 西北工业大学 2024-10-01 CN claimed
CN-117457905-A Binder composition for secondary battery 中国科学院福建物质结构研究所 2024-01-26 CN claimed
CN-116769211-A Low-volume shrinkage and aging-resistant photo-curing release film and preparation process thereof 苏州鸿科新材料科技有限公司 2023-09-19 CN claimed
CN-109071966-B Coating layer P2I有限公司 2022-07-22 CN claimed
US-20210368632-A1 METHOD FOR FORMING A COATING ON AN ELECTRONIC OR ELECTRICAL DEVICE P2I LTD (GB) 2021-11-25 US claimed
WO-2017153747-A1 BARRIER COATED SUBSTRATES FLEXIBLE BARRIER FILMS LIMITED (GB) 2017-09-14 WO claimed
EP-2276781-B1 ETHYLENE-TETRAFLUOROETHYLENE INTERMEDIATES DU PONT (US) 2012-11-07 EP claimed
US-8212064-B2 Ethylene tetrafluoroethylene intermediates E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-07-03 US claimed
US-20090305071-A1 Fluoro-compound water repellent composition for wood product dimensional stability ZHANG JUN 2009-12-10 US claimed
US-20090287010-A1 Ethylene-tetrafluoroethylene intermediates E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-11-19 US claimed
US-20070160850-A1 Fluoro-compound water repellent composition for wood product dimensional stability OSMOSE, INC. (US) 2007-07-12 US claimed
WO-2007067648-A2 FLUORO-COMPOUND WATER REPELLENT COMPOSITION FOR WOOD PRODUCT DIMENSIONAL STABILITY OSMOSE, INC. (US) 2007-06-14 WO claimed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528966-B2 Coatings C9, SDC1, CD59 THRB 2283/4885ALDH1A1 1446/4885TP53 4726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.