SCHEMBL528801

SCHEMBL528801

C=CC(=O)OC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.37
ALDH1A1 P00352 4/20 0.31
TP53 P04637 3/20 0.31
HIF1A Q16665 3/20 0.31
CYP3A4 P08684 2/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TSHR P16473 4/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1536830 1.00 THRB (0.37) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL11792087 1.00 THRB (0.37) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL1536941 1.00 THRB (0.37) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL1516375 1.00 THRB (0.37) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL534358 1.00 THRB (0.37) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL1536946 1.00 THRB (0.37) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL1537075 1.00 THRB (0.37) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL535075 1.00 THRB (0.37) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL1536821 1.00 THRB (0.37) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL5087400 1.00 THRB (0.37) THRBALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080419-A Stabilizer for preparing polycaprolactone and application thereof 2026-05-26 CN claimed
CN-122091709-A Composite solid electrolyte, preparation method thereof and secondary battery containing composite solid electrolyte 2026-05-26 CN claimed
CN-117430746-B Janus particle based on GMA monomer emulsion polymerization and preparation method and application thereof 江苏大学 2026-05-19 CN claimed
CN-122006505-A Durable superhydrophobic uniform pore separation membrane and preparation method and application thereof 沧州市天津工业大学研究院 2026-05-12 CN claimed
CN-122011872-A PVB resin-based anti-corrosion weather-resistant coating and preparation method thereof 江西天城高新材料有限公司 2026-05-12 CN claimed
EP-4735935-A2 SURFACE ACTIVATED CHEMICAL VAPOR DEPOSITION AND USES THEREOF Gvd Corporation (US) 2026-05-06 EP claimed
EP-4735934-A2 SURFACE ACTIVATED CHEMICAL VAPOR DEPOSITION AND USES THEREOF Gvd Corporation (US) 2026-05-06 EP claimed
EP-4735933-A2 SURFACE ACTIVATED CHEMICAL VAPOR DEPOSITION AND USES THEREOF Gvd Corporation (US) 2026-05-06 EP claimed
EP-3573461-B1 ANTIMICROBIAL, NON-THROMBOGENIC POLYMER COMPOSITIONS LUBRIZOL ADVANCED MAT INC (US) 2026-04-22 EP claimed
US-12528966-B2 Coatings P2I LTD (GB) 2026-01-20 US claimed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed
US-6136896-A Graft copolymers containing polydiorganosiloxane and polybutylene grafts DOW CORNING CORPORATION (US) 2000-10-24 US claimed
EP-0425436-B1 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA GEIGY AG (CH) 1996-12-27 EP claimed
US-5239026-A Curable fluorinated acrylates, adhesion promoters; silane coupler MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-24 US claimed
US-5152287-A Cross-linked fluorinated polymers for use in gas sensors CORDIS CORPORATION (US) 1992-10-06 US claimed
EP-0425436-A2 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA-GEIGY AG (CH) 1991-05-02 EP claimed
US-5010141-A Heat- or UV-curable acrylic resins; coatings; films; biocompatible, water-swelling, oxygen-permeable contact lenses CIBA-GEIGY CORPORATION (US) 1991-04-23 US claimed
US-4387203-A COPOLYMER OF AN UNSATURATED NITRILE, CONJUGATED DIENE AND UNSATURATED FLUORINE COMPOUND GASOLINE RESISTANCE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-06-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528966-B2 Coatings C9, SDC1, CD59 THRB 2283/4885ALDH1A1 1446/4885TP53 4726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.