Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 10/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 9/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5088070 | 0.87 | ALDH1A1 (0.52) | EGFRBRAFCSNK2A1CSNK2A2CSNK2B | |
| Hydrochloric Acid SCHEMBL5081843 | 0.84 | KDM4E (0.39) | MEN1KMT2ACNR2 | |
| SCHEMBL5250340 | 0.81 | TTBK1 (0.48) | EGFRCSNK2A1CSNK2A2CSNK2BMEN1 | |
| Hydrochloric Acid SCHEMBL4764835 | 0.77 | HAO1 (0.43) | EGFRCSNK2A2CSNK2B | |
| SCHEMBL16146826 | 0.74 | BRAF (0.51) | EGFRBRAFCSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL10488935 | 0.72 | EGFR (0.54) | EGFRCSNK2A1CSNK2A2CSNK2BMEN1 | |
| SCHEMBL16146884 | 0.72 | BRAF (0.51) | EGFRBRAFCSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL3001568 | 0.71 | BRAF (0.53) | EGFRBRAFMEN1KMT2A | |
| SCHEMBL16146827 | 0.71 | BRAF (0.73) | BRAFPDPK1JAK2CDK2FLT3 | |
| SCHEMBL30523411 | 0.71 | BRAF (0.73) | BRAFPDPK1JAK2CDK2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008116816-A1 | COMBINATION OF CB2 LIGAND AND PARACETAMOL | GLAXO GROUP LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |