Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | BRAF | P15056 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5087476 | 0.87 | EGFR (0.49) | BRAFKMT2AEGFRMEN1CSNK2A2 | |
| SCHEMBL5087486 | 0.76 | KDM4E (0.43) | ALDH1A1MAPTKDM4EHPGDNPC1 | |
| SCHEMBL10488563 | 0.75 | SMN1; SMN2 (0.56) | ALDH1A1MAPTKDM4EALOX5PTGES | |
| SCHEMBL4898607 | 0.74 | BRAF (0.61) | ALDH1A1MAPTKDM4EBRAFHPGD | |
| SCHEMBL3993488 | 0.71 | MAPT (0.55) | ALDH1A1MAPTKDM4EALOX5PTGES | |
| SCHEMBL28426697 | 0.70 | MEN1 (0.60) | ALDH1A1MAPTKDM4EALOX5PTGES | |
| SCHEMBL16146826 | 0.70 | BRAF (0.51) | BRAFKMT2AEGFRMEN1CSNK2A2 | |
| SCHEMBL9896825 | 0.70 | JAK3 (0.68) | EGFRJAK2JAK3 | |
| Hydrochloric Acid SCHEMBL9896822 | 0.69 | JAK3 (0.67) | EGFRJAK2JAK3 | |
| SCHEMBL5250340 | 0.69 | TTBK1 (0.48) | ALDH1A1KMT2AEGFRMEN1CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008116816-A1 | COMBINATION OF CB2 LIGAND AND PARACETAMOL | GLAXO GROUP LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |