Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | AVPR1B | P47901 | 5/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5087475 | 0.82 | F2 (0.40) | NMT1F2AVPR1BAVPR1AMEN1 | |
| SCHEMBL492918 | 0.77 | F2 (0.39) | NMT1F2AVPR1BAVPR1AMEN1 | |
| SCHEMBL644441 | 0.72 | NMT1 (0.41) | NMT1F2AVPR1BAVPR1ATAAR1 | |
| SCHEMBL114242 | 0.70 | NMT1 (0.49) | NMT1F2NR3C1PGRNR3C2 | |
| SCHEMBL29381119 | 0.70 | NMT1 (0.49) | NMT1F2NR3C1PGRNR3C2 | |
| SCHEMBL4084739 | 0.70 | F2 (0.34) | NMT1F2AVPR1BAVPR1AEPHX2 | |
| SCHEMBL27544457 | 0.69 | NMT1 (0.51) | NMT1F2AVPR1BAVPR1ANR3C1 | |
| SCHEMBL8295856 | 0.68 | NMT1 (0.50) | NMT1F2AVPR1BNR3C1PGR | |
| SCHEMBL248149 | 0.68 | NMT1 (0.50) | NMT1F2AVPR1BAVPR1ANR3C1 | |
| SCHEMBL4000323 | 0.68 | TSHR (0.40) | MEN1KMT2ASLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312231-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312231-A1 | Substituted Sulfonamide Compounds | SULT2A1, SULT1A1, SCN1A | NMT1 2800/4885F2 1898/4885AVPR1B 878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.