Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 6/20 | 0.62 |
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3497943 | 0.87 | SMN1; SMN2 (0.84) | SMN1; SMN2ALDH1A1HPGDPOLBTSHR | |
| SCHEMBL10535954 | 0.83 | SMN1; SMN2 (0.82) | SMN1; SMN2ALDH1A1HPGDPOLBTSHR | |
| SCHEMBL13164429 | 0.82 | SMN1; SMN2 (0.80) | SMN1; SMN2ALDH1A1HPGDPOLBTSHR | |
| SCHEMBL14155879 | 0.82 | SMN1; SMN2 (0.80) | SMN1; SMN2ALDH1A1HPGDPOLBTSHR | |
| SCHEMBL144880 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1HPGDPOLBTSHR | |
| SCHEMBL29367809 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1HPGDPOLBTSHR | |
| SCHEMBL29229036 | 0.80 | SMN1; SMN2 (0.97) | SMN1; SMN2ALDH1A1HPGDPOLBTSHR | |
| SCHEMBL6141647 | 0.79 | CYP1A2 (0.83) | SMN1; SMN2ALDH1A1HPGDPOLBTSHR | |
| SCHEMBL8412717 | 0.78 | CYP1A2 (0.75) | SMN1; SMN2ALDH1A1HPGDPOLBTSHR | |
| SCHEMBL28621136 | 0.78 | CYP1A2 (0.75) | SMN1; SMN2ALDH1A1HPGDPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080145545-A1 | METAL OXIDE AND SULFUR-CONTAINING COATING COMPOSITIONS, METHODS OF USE, AND ARTICLES PREPARED THEREFROM | CITIBANK, N.A., AS COLLATERAL AGENT | 2008-06-19 | — | — | US | disclosed |