SCHEMBL3497943

SCHEMBL3497943

O=C(O)CCCSc1nc2ccccc2s1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 6/20 0.84
ALDH1A1 P00352 5/20 0.84
POLB P06746 3/20 0.84
HPGD P15428 3/20 0.84
TSHR P16473 2/20 0.84
MAPK1 P28482 2/20 0.84
HSD17B10 Q99714 1/20 0.84
LMNA P02545 6/20 0.67
HTT P42858 4/20 0.67
RAB9A P51151 3/20 0.67
NPC1 O15118 2/20 0.67
RECQL P46063 2/20 0.67
CYP1A2 P05177 1/20 0.67
CYP2D6 P10635 1/20 0.67
MAPT P10636 4/20 0.65
L3MBTL1 Q9Y468 2/20 0.65
KDM4E B2RXH2 1/20 0.64
ATM Q13315 1/20 0.63
APEX1 P27695 1/20 0.62
ALOX5 P09917 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10535954 0.96 SMN1; SMN2 (0.82) SMN1; SMN2ALDH1A1POLBHPGDTSHR
SCHEMBL14155879 0.94 SMN1; SMN2 (0.80) SMN1; SMN2ALDH1A1POLBHPGDTSHR
SCHEMBL13164429 0.94 SMN1; SMN2 (0.80) SMN1; SMN2ALDH1A1POLBHPGDTSHR
SCHEMBL29367809 0.91 SMN1; SMN2 (1.00) SMN1; SMN2ALDH1A1POLBHPGDTSHR
SCHEMBL144880 0.91 SMN1; SMN2 (1.00) SMN1; SMN2ALDH1A1POLBHPGDTSHR
SCHEMBL29229036 0.90 SMN1; SMN2 (0.97) SMN1; SMN2ALDH1A1POLBHPGDTSHR
SCHEMBL5087686 0.87 SMN1; SMN2 (0.67) SMN1; SMN2ALDH1A1POLBHPGDTSHR
SCHEMBL6274961 0.84 SMN1; SMN2 (0.85) SMN1; SMN2ALDH1A1POLBHPGDTSHR
SCHEMBL10307829 0.83 SMN1; SMN2 (0.66) SMN1; SMN2ALDH1A1POLBHPGDTSHR
SCHEMBL6141647 0.83 CYP1A2 (0.83) SMN1; SMN2ALDH1A1POLBHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4568753-A Rust-preventive agent SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1986-02-04 US claimed
US-10899935-B2 Coating material for prevention of metal corrosion, and process for producing coating film for prevention of metal corrosion SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-01-26 US disclosed
CN-107834117-B Secondary battery, battery pack, and vehicle 株式会社东芝 2020-12-29 CN disclosed
EP-3345977-B1 COATING MATERIAL FOR PREVENTION OF METAL CORROSION, AND PROCESS FOR PRODUCING COATING FILM FOR PREVENTION OF METAL CORROSION SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed
US-10461370-B2 Secondary battery, battery pack, and vehicle KABUSHIKI KAISHA TOSHIBA (JP) 2019-10-29 US disclosed
US-20180244929-A1 COATING MATERIAL FOR PREVENTION OF METAL CORROSION, AND PROCESS FOR PRODUCING COATING FILM FOR PREVENTION OF METAL CORROSION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-08-30 US disclosed
EP-3345977-A1 COATING MATERIAL FOR PREVENTION OF METAL CORROSION, AND PROCESS FOR PRODUCING COATING FILM FOR PREVENTION OF METAL CORROSION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-07-11 EP disclosed
US-20180083321-A1 SECONDARY BATTERY, BATTERY PACK, AND VEHICLE KABUSHIKI KAISHA TOSHIBA (JP) 2018-03-22 US disclosed
US-20100130737-A1 Regulating Agent of GPR34 Receptor Function TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-05-27 US disclosed
EP-1344055-A4 MATERIALS FOR ENHANCING STAINING OF BIOPOLYMERS IN MATRICES INVITROGEN CORP (US) 2009-03-25 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
EP-0375614-B1 CORROSION-INHIBITING COATING COMPOSITIONS CIBA-GEIGY AG (CH) 1993-03-31 EP disclosed
US-5198482-A Benzothiazole carboxylic acid amine salt CIBA-GEIGY CORPORATION (US) 1993-03-30 US disclosed
EP-0375614-A1 Corrosion-inhibiting coating compositions CIBA-GEIGY AG (CH) 1990-06-27 EP disclosed
US-4762848-A IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1988-08-09 US disclosed
US-4696763-A PAINTS, BLENDS CIBA-GEIGY CORPORATION (US) 1987-09-29 US disclosed
EP-0194572-A1 Heterocyclic sulfides, process for their preparation and Medicaments containing them HOECHST AKTIENGESELLSCHAFT (DE) 1986-09-17 EP disclosed
US-4612049-A BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID CIBA-GEIGY CORPORATION (US) 1986-09-16 US disclosed
US-4568753-A Rust-preventive agent SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1986-02-04 US disclosed
EP-0137426-A2 2-Mercaptothiazole derivatives, process for their preparation and utilization of 2-mercaptothiazole derivatives in pharmaceutical compounds BAYER AG (DE) 1985-04-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100130737-A1 Regulating Agent of GPR34 Receptor Function GPR34, GPR4, GPR6 SMN1; SMN2 4779/4885ALDH1A1 3047/4885POLB 4658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.