Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.30 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.30 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27566834 | 0.92 | CYP2C19 (0.37) | LMNACYP2C19ALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL11149812 | 0.89 | LMNA (0.41) | LMNACYP2C19ALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL11149814 | 0.83 | CYP2C19 (0.35) | LMNACYP2C19SMN1; SMN2TSHR | |
| SCHEMBL11873552 | 0.82 | LMNA (0.43) | LMNAEGLN1CYP2C19KDM6BKDM5C | |
| SCHEMBL29214073 | 0.82 | NAAA (0.37) | LMNACYP2C19SMN1; SMN2TSHR | |
| SCHEMBL29214071 | 0.82 | NAAA (0.37) | LMNACYP2C19SMN1; SMN2TSHR | |
| SCHEMBL4396634 | 0.80 | ALDH1A1 (0.43) | LMNACYP2C19ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL25397837 | 0.78 | CYP19A1 (0.47) | LMNAEGLN1CYP2C19KDM6BKDM5C | |
| SCHEMBL29519107 | 0.77 | NAAA (0.41) | LMNAALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL27465776 | 0.75 | SMN1; SMN2 (0.38) | LMNACYP2C19ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105542134-B | A kind of lactyl aliphatic aromatic random copolymer | 中国科学院长春应用化学研究所 | 2017-11-28 | — | — | CN | disclosed |
| CN-101223129-A | Highly selective serotonin and norepinephrine dual reuptake inhibitor and use thereof | WYETH CORP (US) | 2008-07-16 | — | — | CN | disclosed |
| EP-1904434-A2 | HIGHLY SELECTIVE SEROTONIN AND NOREPINEPHRINE DUAL REUPTAKE INHIBITOR AND USE THEREOF | Wyeth a Corporation of the State of Delaware (US) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007011594-A2 | HIGHLY SELECTIVE SEROTONIN AND NOREPINEPHRINE DUAL REUPTAKE INHIBITOR AND USE THEREOF | WYETH (US) | 2007-01-25 | — | — | WO | disclosed |