Hydrochloric Acid

Hydrochloric Acid

SCHEMBL5087717

CC[P+](CC)(c1ccccc1)c1ccccc1.[Cl-]

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.43
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.39
ESR1 P03372 1/20 0.36
TRPA1 O75762 1/20 0.35
TSHR P16473 2/20 0.34
MIF P14174 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ALDH1A1 P00352 2/20 0.33
ADORA1 P30542 1/20 0.33
KDM4E B2RXH2 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MAOA P21397 1/20 0.33
GPR84 Q9NQS5 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
HKDC1 Q2TB90 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL2029525 0.94 HIF1A (0.43) HIF1ALMNATP53ESR1TRPA1
Bromide SCHEMBL5088201 0.94 HIF1A (0.43) HIF1ALMNATP53ESR1TRPA1
Water SCHEMBL2032977 0.94 HIF1A (0.43) HIF1ALMNATP53ESR1TRPA1
SCHEMBL7871179 0.92 HIF1A (0.42) HIF1ALMNATP53ESR1TRPA1
SCHEMBL7865391 0.90 HIF1A (0.40) HIF1ALMNATP53ESR1TRPA1
Phenol SCHEMBL7865420 0.85 HIF1A (0.37) HIF1ALMNATP53ESR1TRPA1
SCHEMBL4383948 0.84 HIF1A (0.36) HIF1ALMNATP53ESR1TRPA1
Acetic Acid SCHEMBL7874620 0.82 CES2 (0.41) LMNATSHRMEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL5091739 0.79 HIF1A (0.46) HIF1ALMNATP53TSHRALDH1A1
Hydrochloric Acid SCHEMBL2965186 0.78 HIF1A (0.43) HIF1ALMNATP53ESR1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316575-B1 MELT TRANSESTERIFICATION OF DIOL COMPOUND AND CARBOANTE COMPOUND USING CATALYST COMPRISING A PHOSPHORUS-CONTAINING BASIC COMPOUND QUATERNARY PHOSPHONIUM SALT TO FORM POLYCARBONATE IDEMITSU KOSAN CO., LTD. (JP) 2001-11-13 US claimed
US-20080214386-A1 Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2008-09-04 US disclosed
EP-0834496-B1 Preparation of diaryl carbonate UBE INDUSTRIES (JP) 2001-08-16 EP disclosed
EP-0834495-B1 Process for preparing diaryl carbonate UBE INDUSTRIES (JP) 2000-12-27 EP disclosed
US-5892091-A PHOSPHOROUS CATALYSTS AND HALOGEN ATOMS UBE INDUSTRIES, LTD. (JP) 1999-04-06 US disclosed
US-5892089-A FROM DIARYL OXALATE IN LIQUID PHASE BY DECARBONYLATION USING ORGANIC PHOSHORUS COMPOUND CATALYST UBE INDUSTRIES, LTD. (JP) 1999-04-06 US disclosed
EP-0737665-B1 Process for preparation of diaryl carbonate UBE INDUSTRIES (JP) 1998-10-21 EP disclosed
US-5792883-A Preparation of diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1998-08-11 US disclosed
EP-0834496-A1 Preparation of diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1998-04-08 EP disclosed
EP-0834495-A1 Process for preparing diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1998-04-08 EP disclosed
EP-0826658-A1 Catalyst for decarbonylation reaction UBE INDUSTRIES, LTD. (JP) 1998-03-04 EP disclosed
US-5648510-A DECARBONYLATION OF OXALATE UBE INDUSTRIES, LTD. (JP) 1997-07-15 US disclosed
EP-0737665-A1 Process for preparation of diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1996-10-16 EP disclosed