Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL679805 | 0.94 | HIF1A (0.43) | HIF1ALMNATP53ESR1TRPA1 | |
| Iodide SCHEMBL5085335 | 0.94 | HIF1A (0.43) | HIF1ALMNATP53ESR1TRPA1 | |
| Fluoride Ion SCHEMBL4618615 | 0.94 | HIF1A (0.43) | HIF1ALMNATP53ESR1TRPA1 | |
| SCHEMBL9752172 | 0.94 | HIF1A (0.43) | HIF1ALMNATP53ESR1TRPA1 | |
| Water SCHEMBL2822588 | 0.94 | HIF1A (0.43) | HIF1ALMNATP53ESR1TRPA1 | |
| Hydrochloric Acid SCHEMBL5180858 | 0.85 | HIF1A (0.42) | HIF1ALMNATP53ESR1TRPA1 | |
| Hydrochloric Acid SCHEMBL11787411 | 0.84 | TRPA1 (0.42) | TP53TRPA1ADORA1MAOACYP1A2 | |
| SCHEMBL9752213 | 0.84 | HIF1A (0.36) | HIF1ALMNATP53ESR1TSHR | |
| SCHEMBL8206187 | 0.84 | LMNA (0.39) | HIF1ALMNAMEN1KMT2AALDH1A1 | |
| Benzil SCHEMBL21852689 | 0.83 | CES2 (0.54) | LMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698332-A | GLYCIDYL (METH)ACRYLATE; LATENT CATALYST | THE DOW CHEMICAL COMPANY (US) | 1997-12-16 | — | — | US | claimed |
| US-5698641-A | INCLUDES A CATALYST AND A SURFACTANT OR FLOW CONTROL AGENT | THE DOW CHEMICAL COMPANY (US) | 1997-12-16 | — | — | US | claimed |
| US-5633330-A | Coating composition of non-cyclic polyanhydride and glycidyl oligomer | THE DOW CHEMICAL COMPANY (US) | 1997-05-27 | — | — | US | claimed |
| US-5633020-A | Coating composition of non-cyclic polyanhydride and co-reactant resin | THE DOW CHEMICAL COMPANY (US) | 1997-05-27 | — | — | US | claimed |
| US-11192329-B2 | Decorative sheet with adhesive | AICA KOGYO CO., LTD. (JP) | 2021-12-07 | — | — | US | disclosed |
| US-10815395-B2 | Decorative sheet | AICA KOGYO CO., LTD. (JP) | 2020-10-27 | — | — | US | disclosed |
| CN-107848263-B | Decorative sheet | 爱克工业株式会社 | 2020-10-09 | — | — | CN | disclosed |
| US-20200122428-A1 | DECORATIVE SHEET WITH ADHESIVE | AICA KOGYO CO., LTD. (JP) | 2020-04-23 | — | — | US | disclosed |
| US-20180201810-A1 | DECORATIVE SHEET | AICA KOGYO CO., LTD. (JP) | 2018-07-19 | — | — | US | disclosed |
| EP-1238704-B1 | Catalyst comprising a cyclic imide compound and process for producing organic compounds using the catalyst | DAICEL CHEM (JP) | 2015-01-21 | — | — | EP | disclosed |
| EP-1754693-B9 | Process for the production of esters or lactones | DAICEL CHEM (JP) | 2013-08-14 | — | — | EP | disclosed |
| EP-1754693-B1 | Process for the production of esters or lactones | DAICEL CHEM (JP) | 2013-02-06 | — | — | EP | disclosed |
| US-4496779-A | Process for the hydroxylation of olefins using molecular oxygen, an osmium containing catalyst, a copper co-catalyst, and a cycloaliphatic amine based promoter | EXXON RESEARCH & ENGINEERING CO. (US) | 1985-01-29 | — | — | US | disclosed |
| US-4486613-A | CATALYTIC OXIDATION | EXXON RESEARCH & ENGINEERING CO. (US) | 1984-12-04 | — | — | US | disclosed |
| EP-0104873-A2 | A process for hydroxylating olefins using an osmium carbonyl catalyst | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1984-04-04 | — | — | EP | disclosed |
| EP-0102154-A1 | Process for hydroxylating olefins using a supported osmium catalyst | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1984-03-07 | — | — | EP | disclosed |
| US-4413151-A | WITH WATER AND OXIDIZER | EXXON RESEARCH & ENGINEERING CO. (US) | 1983-11-01 | — | — | US | disclosed |
| US-4390739-A | Hydroxylation of olefins | EXXON RESEARCH & ENGINEERING CO. (US) | 1983-06-28 | — | — | US | disclosed |
| EP-0077202-A2 | Process for hydroxylating olefins using osmium-halogen compound catalysts | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1983-04-20 | — | — | EP | disclosed |
| EP-0077201-A2 | Hydroxylation of olefins | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1983-04-20 | — | — | EP | disclosed |