Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.36 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL9550579 | 0.81 | KDM4E (0.38) | TSHRSMN1; SMN2ALDH1A1HPGDRAB9A | |
| SCHEMBL9581630 | 0.81 | CCR6 (0.40) | TSHRSMN1; SMN2PDK2ALDH1A1HPGD | |
| SCHEMBL9665033 | 0.81 | NPC1 (0.35) | TSHRSMN1; SMN2PDK2ALDH1A1HPGD | |
| SCHEMBL9582596 | 0.81 | TP53 (0.40) | TSHRSMN1; SMN2PDK2ALDH1A1HPGD | |
| SCHEMBL9581427 | 0.81 | KDM4E (0.39) | TSHRSMN1; SMN2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL10990741 | 0.80 | ABCC9 (0.48) | TSHRSMN1; SMN2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL9582054 | 0.80 | USP2 (0.36) | TSHRSMN1; SMN2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL9664058 | 0.80 | ALDH1A1 (0.39) | TSHRSMN1; SMN2PDK2ALDH1A1HPGD | |
| SCHEMBL9664156 | 0.80 | HDAC3 (0.34) | TSHRSMN1; SMN2PDK2ALDH1A1HPGD | |
| SCHEMBL9755660 | 0.79 | ABCC9 (0.37) | TSHRSMN1; SMN2PDK2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008099175-A1 | CAMP DEPENDENT INDUCTION OF AUTOPHAGY | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2008-08-21 | — | — | WO | disclosed |