Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 2/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 4/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9664058 | 0.88 | ALDH1A1 (0.39) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL10990741 | 0.88 | ABCC9 (0.48) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9582596 | 0.81 | TP53 (0.40) | CYP1A2CYP2D6CYP2C9CYP2C19LMNA | |
| Dimethylamine SCHEMBL9550579 | 0.81 | KDM4E (0.38) | CYP1A2CYP2D6CYP2C9CYP2C19LMNA | |
| SCHEMBL9665033 | 0.81 | NPC1 (0.35) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9581630 | 0.81 | CCR6 (0.40) | CYP1A2CYP2D6CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9581427 | 0.80 | KDM4E (0.39) | CYP1A2CYP2D6CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9664156 | 0.80 | HDAC3 (0.34) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9582054 | 0.80 | USP2 (0.36) | CYP1A2CYP2D6CYP2C9CYP2C19LMNA | |
| SCHEMBL5087790 | 0.79 | TSHR (0.42) | CYP1A2CYP2D6CYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991011446-A1 | BENZOPYRANS HAVING PHARMACOLOGICAL ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-08-08 | — | — | WO | claimed |
| WO-1991011446-A1 | BENZOPYRANS HAVING PHARMACOLOGICAL ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-08-08 | — | — | WO | disclosed |