Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 2/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5087983 | 1.00 | ATM (0.39) | ATMCASP1CASP3CASP7CASP6 | |
| SCHEMBL14290495 | 0.86 | HTR2A (0.35) | — | |
| SCHEMBL4950109 | 0.83 | ATM (0.39) | ATMCASP1CASP3CASP7CASP6 | |
| SCHEMBL4950100 | 0.83 | ATM (0.39) | ATMCASP1CASP3CASP7CASP6 | |
| SCHEMBL4951270 | 0.83 | ATM (0.39) | ATMCASP1CASP3CASP7CASP6 | |
| SCHEMBL4951359 | 0.82 | ATM (0.42) | ATMCAPN1CYP1A2CTSSCTSK | |
| SCHEMBL4951396 | 0.77 | ATM (0.43) | ATMCTSLCTSSCTSK | |
| SCHEMBL5637368 | 0.77 | ATM (0.43) | ATMCTSLCTSSCTSK | |
| SCHEMBL3962356 | 0.76 | ATM (0.43) | ATMCTSLCTSSCTSK | |
| SCHEMBL4780653 | 0.76 | HTR2C (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080033183-A1 | PROCESS FOR PREPARING PYRANOINDAZOLE SEROTONERGIC RECEPTOR AGONISTS | ALCON MANUFACTURING, LTD. (US) | 2008-02-07 | — | — | US | claimed |
| US-20080033183-A1 | PROCESS FOR PREPARING PYRANOINDAZOLE SEROTONERGIC RECEPTOR AGONISTS | ALCON MANUFACTURING, LTD. (US) | 2008-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080033183-A1 | PROCESS FOR PREPARING PYRANOINDAZOLE SEROTONERGIC RECEPTOR AGONISTS | HTR3A, HTR3C, HTR7 | ATM 3994/4885CASP1 614/4885CASP3 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.