Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 5/20 | 0.58 |
| ▸ | CES1 | P23141 | 5/20 | 0.58 |
| ▸ | GLS | O94925 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5087988 | 1.00 | CES2 (0.58) | CES2CES1GLSKMT2AMEN1 | |
| SCHEMBL7522990 | 0.86 | CES2 (0.56) | CES2CES1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8410789 | 0.86 | CES2 (0.56) | CES2CES1KMT2AMEN1ALDH1A1 | |
| SCHEMBL31494830 | 0.84 | CES2 (0.47) | CES2CES1KMT2AMEN1BCHE | |
| SCHEMBL26690540 | 0.83 | CASP1 (0.41) | CES2CES1KMT2ALMNA | |
| SCHEMBL5085041 | 0.81 | CES2 (0.45) | CES2CES1GLSKMT2AMEN1 | |
| SCHEMBL21379847 | 0.80 | CES2 (0.56) | CES2CES1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9890656 | 0.80 | CES2 (0.42) | CES2CES1KMT2AMEN1ALDH1A1 | |
| SCHEMBL23972274 | 0.78 | CES2 (0.66) | CES2CES1GLSKMT2ABCHE | |
| SCHEMBL31407017 | 0.78 | CES2 (0.66) | CES2CES1GLSKMT2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008078350-A2 | PROCESS FOR THE PREPARATION OF FLUOROPHENYLACETIC ACIDS AND DERIVATIVES THEREOF | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2008-07-03 | — | — | WO | disclosed |