Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14336848 | 0.86 | POLB (0.35) | THRBHCAR2CYP2C19POLBAKT1 | |
| SCHEMBL1493626 | 0.83 | ATM (0.41) | THRBHCAR2CYP2C19AKT1L3MBTL1 | |
| SCHEMBL14336588 | 0.81 | MEN1 (0.37) | THRBHCAR2CYP2C19POLBL3MBTL1 | |
| SCHEMBL8213806 | 0.81 | POLB (0.38) | HCAR2CYP2C19POLBNPSR1L3MBTL1 | |
| SCHEMBL27801809 | 0.80 | POLB (0.41) | POLBNPSR1L3MBTL1GAAMAPK1 | |
| SCHEMBL14336589 | 0.80 | HCAR2 (0.35) | THRBHCAR2KMT2A | |
| SCHEMBL5932732 | 0.79 | POLB (0.40) | POLBNPSR1L3MBTL1GAAMAPK1 | |
| SCHEMBL5087975 | 0.78 | HCAR2 (0.41) | THRBHCAR2CYP2C19AKT1KMT2A | |
| SCHEMBL29387790 | 0.78 | THRB (0.35) | THRBHCAR2CYP2C19AKT1L3MBTL1 | |
| SCHEMBL11223311 | 0.77 | CYP2D6 (0.42) | POLBNPSR1L3MBTL1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831305-B1 | GRAFT COPOLYMERS WITH SEGMENTED ARMS | COATINGS FOREIGN IP CO LLC (US) | 2015-08-12 | — | — | EP | disclosed |
| US-7402624-B2 | Graft copolymers with segmented arms and their preparation and use | E.I. DU PONT DE NEMOURS & COMPANY (US) | 2008-07-22 | — | — | US | disclosed |
| EP-1831305-A2 | GRAFT COPOLYMERS WITH SEGMENTED ARMS AND THEIR PREPARATION AND USE | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006052981-A2 | GRAFT COPOLYMERS WITH SEGMENTED ARMS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-05-18 | — | — | WO | disclosed |
| US-20060100305-A1 | Graft copolymers with segmented arms and their preparation and use | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2006-05-11 | — | — | US | disclosed |