Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4595706 | 0.83 | HCAR2 (0.46) | HCAR2THRBHTTCYP2C19KMT2A | |
| SCHEMBL24708816 | 0.82 | THRB (0.43) | HCAR2THRBCYP2C19KMT2ACYP3A4 | |
| SCHEMBL5091148 | 0.79 | HPGD (0.38) | HCAR2HTTKMT2ACYP3A4MEN1 | |
| SCHEMBL5088009 | 0.78 | THRB (0.38) | HCAR2THRBCYP2C19KMT2AAKT1 | |
| SCHEMBL5580239 | 0.78 | KDM4E (0.45) | HCAR2THRBCYP2C19KMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL7722976 | 0.77 | ALDH1A1 (0.44) | HCAR2THRBCYP2C19KMT2ACYP3A4 | |
| SCHEMBL28863896 | 0.76 | HCAR2 (0.67) | HCAR2THRBCYP2C19KMT2ACYP3A4 | |
| SCHEMBL41557 | 0.76 | HCAR2 (0.67) | HCAR2THRBCYP2C19KMT2ACYP3A4 | |
| SCHEMBL2399072 | 0.75 | HCAR2 (0.40) | HCAR2HTTCYP2C19KMT2ACYP3A4 | |
| SCHEMBL27822148 | 0.75 | CYP2D6 (0.52) | HCAR2THRBCYP2C19KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831305-B1 | GRAFT COPOLYMERS WITH SEGMENTED ARMS | COATINGS FOREIGN IP CO LLC (US) | 2015-08-12 | — | — | EP | disclosed |
| US-7402624-B2 | Graft copolymers with segmented arms and their preparation and use | E.I. DU PONT DE NEMOURS & COMPANY (US) | 2008-07-22 | — | — | US | disclosed |
| EP-1831305-A2 | GRAFT COPOLYMERS WITH SEGMENTED ARMS AND THEIR PREPARATION AND USE | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006052981-A2 | GRAFT COPOLYMERS WITH SEGMENTED ARMS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-05-18 | — | — | WO | disclosed |
| US-20060100305-A1 | Graft copolymers with segmented arms and their preparation and use | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2006-05-11 | — | — | US | disclosed |