Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 9/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315867 | 0.71 | FTO (0.45) | FTOHPGDHTTMEN1MAPT | |
| SCHEMBL1032050 | 0.71 | FTO (0.74) | FTOHPGDHTTMEN1MAPT | |
| SCHEMBL6511956 | 0.70 | FTO (0.50) | FTOHPGDHTTMEN1MAPT | |
| SCHEMBL29438543 | 0.68 | FTO (0.45) | FTOHPGDHTTMEN1MAPT | |
| SCHEMBL1650598 | 0.68 | FTO (0.45) | FTOHPGDHTTMEN1MAPT | |
| SCHEMBL8571494 | 0.66 | FTO (0.71) | FTOHPGDHTTMEN1MAPT | |
| SCHEMBL12986496 | 0.63 | FTO (0.43) | FTOHPGDHTTMEN1MAPT | |
| SCHEMBL3844808 | 0.62 | FTO (0.34) | FTOHPGDHTTMEN1MAPT | |
| SCHEMBL3705213 | 0.62 | FTO (0.44) | FTOHPGDHTTMEN1MAPT | |
| SCHEMBL7521638 | 0.62 | FTO (0.53) | FTOHPGDHTTMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358052-B2 | Catalytic amplification of multiplexed assay signals | MONOGRAM BIOSCIENCES, INC. (US) | 2008-04-15 | — | — | US | disclosed |
| US-20060025335-A1 | Netrin compositions and methods of using the same | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2006-02-02 | — | — | US | disclosed |
| WO-2005074556-A2 | NETRIN COMPOSITIONS AND METHODS OF USE THEREOF | THE GENERAL HOSPITAL CORPORATION (US) | 2005-08-18 | — | — | WO | disclosed |
| US-20020197649-A1 | Catalytic amplification of multiplexed assay signals | MONOGRAM BIOSCIENCES, INC. | 2002-12-26 | — | — | US | disclosed |
| WO-2002097112-A2 | CATALYTIC AMPLIFICATION OF MULTIPLEXED ASSAY SIGNALS | ACLARA BIOSCIENCES, INC. (US) | 2002-12-05 | — | — | WO | disclosed |
| US-5773236-A | FLUORESCENT DYES FOR DETECTION OF ENZYMES FOR METABOLISM IN CELLS | MOLECULE PROBES, INC. (US) | 1998-06-30 | — | — | US | disclosed |