SCHEMBL29438543

SCHEMBL29438543

O=C(Nc1ccc2c(c1)C(O)OC21c2ccc(O)cc2Oc2cc(O)ccc21)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 5/20 0.45
HTT P42858 2/20 0.42
TSHR P16473 3/20 0.38
ALDH1A1 P00352 5/20 0.37
KLK7 P49862 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.36
NPSR1 Q6W5P4 2/20 0.36
MAPK1 P28482 1/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
KDM4E B2RXH2 2/20 0.36
HSD17B10 Q99714 2/20 0.36
HPGD P15428 2/20 0.36
GLA P06280 1/20 0.36
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36
PPARG P37231 1/20 0.36
NCOA2 Q15596 1/20 0.36
NCOA1 Q15788 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1650598 1.00 FTO (0.45) FTOHTTTSHRALDH1A1KLK7
SCHEMBL1032050 0.78 FTO (0.74) FTOHTTALDH1A1MEN1KMT2A
SCHEMBL8571494 0.73 FTO (0.71) FTOHTTALDH1A1MEN1KMT2A
SCHEMBL20353261 0.72 FTO (0.41) FTOHTTALDH1A1NPSR1MAPK1
SCHEMBL18653597 0.72 FTO (0.52) FTOHTTALDH1A1NPSR1MEN1
SCHEMBL6511956 0.69 FTO (0.50) FTOHTTTSHRALDH1A1NPSR1
SCHEMBL5088010 0.68 FTO (0.39) FTOHTTALDH1A1MEN1KMT2A
SCHEMBL8571885 0.68 FTO (0.57) FTOHTTALDH1A1MEN1KMT2A
SCHEMBL24450328 0.67 FTO (0.36) FTOHTTALDH1A1MEN1KMT2A
SCHEMBL8568046 0.66 FTO (0.77) FTOHTTMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109863161-B Labeled polynucleotides useful for nucleic acid sequencing 豪夫迈·罗氏有限公司 2022-06-03 CN claimed
WO-2026102003-A1 METHODS FOR DETECTING AND DISTINGUISHING TREPONEMA PALLIDUM SUBSPECIES AND USES THEREOF ABBOTT LABORATORIES (US) 2026-05-15 WO disclosed
CN-120051565-A Engineered terminal deoxynucleotidyl transferase variants 科德克希思公司 2025-05-27 CN disclosed
CN-115058313-B Sealing device for connecting amplification and detection reaction systems and use method 固安北吉生物科技有限公司 2025-02-28 CN disclosed
CN-119546765-A Hybrid oligonucleotides 恩特拉达治疗学股份有限公司 2025-02-28 CN disclosed
EP-4416169-A2 A RECOMBINANT REFLECTIN NANOPARTICLE Nanyang Technological University (SG) 2024-08-21 EP disclosed
CN-118475704-A Nucleic acid characterization 剑桥企业有限公司 2024-08-09 CN disclosed
EP-4399206-A1 PAPD5 AND/OR PAPD7 INHIBITING 4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES Redona Therapeutics, Inc. (US) 2024-07-17 EP disclosed
CN-118251490-A Antisense oligonucleotides 奥托泰利克生物公司 2024-06-25 CN disclosed
CN-113272442-B One-pot synthesis of pools of oligonucleotides DNA斯克瑞普特公司 2024-03-15 CN disclosed
CN-116157392-A Compounds targeting RNA binding proteins or RNA modification proteins 雷多纳治疗公司 2023-05-23 CN disclosed
WO-2023069332-A1 CELL PERMEABLE MACROCYCLIC PEPTIDES USEFUL FOR EIF4E CAP-BINDING SITE INHIBITION MERCK SHARP & DOHME LLC (US) 2023-04-27 WO disclosed
WO-2023063890-A2 A RECOMBINANT REFLECTIN NANOPARTICLE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2023-04-20 WO disclosed
WO-2023039089-A1 PAPD5 AND/OR PAPD7 INHIBITING 4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES TWENTYEIGHT-SEVEN, INC. (US) 2023-03-16 WO disclosed
EP-4118432-A1 METHOD FOR DROPLET LOADING INTO NANOWELLS Abbott Laboratories (US) 2023-01-18 EP disclosed
CN-109863161-B Labeled polynucleotides useful for nucleic acid sequencing 豪夫迈·罗氏有限公司 2022-06-03 CN disclosed
WO-2022103947-A2 LACTOTRANSFERRIN AND MIF PROMOTER POLYMORHPISM DETECTION FOR CANCER DETECTION AND TREATMENT THE CLEVELAND CLINIC FOUNDATION (US) 2022-05-19 WO disclosed
WO-2022071581-A1 SARS-COV-2-BINDING PEPTIDE 株式会社Epsilon Molecular Engineering 2022-04-07 WO disclosed
CN-114174509-A Primer, double-stranded DNA production apparatus using the same, and double-stranded DNA production method 国立研究开发法人科学技术振兴机构 2022-03-11 CN disclosed
WO-2022026670-A1 SYSTEM AND SELF-METERING CARTRIDGES FOR POINT OF CARE BIOASSAYS WAINAMICS, INC. (US) 2022-02-03 WO disclosed