SCHEMBL1032050

SCHEMBL1032050

O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccc(NC(=O)c3c(F)c(F)c(F)c(F)c3F)cc21

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FTO Q9C0B1 9/20 0.74
▸ HPGD P15428 2/20 0.57
▸ HTT P42858 2/20 0.57
▸ MEN1 O00255 1/20 0.57
▸ MAPT P10636 1/20 0.57
▸ CYP2C19 P33261 1/20 0.57
▸ RECQL P46063 1/20 0.57
▸ BLM P54132 1/20 0.57
▸ SMAD3 P84022 1/20 0.57
▸ KMT2A Q03164 1/20 0.57
▸ PRMT1 Q99873 1/20 0.57
▸ ACE2 Q9BYF1 1/20 0.57
▸ TDP1 Q9NUW8 1/20 0.57
▸ JAK2 O60674 2/20 0.47
▸ DRD1 P21728 2/20 0.47
▸ MAPK10 P53779 2/20 0.46
▸ MAPK14 Q16539 2/20 0.46
▸ NAALAD2 Q9Y3Q0 1/20 0.46
▸ KDM4E B2RXH2 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8571494 0.94 FTO (0.71) FTOHPGDHTTMEN1MAPT
SCHEMBL8568046 0.88 FTO (0.77) FTOHPGDHTTMEN1MAPT
SCHEMBL7973230 0.88 FTO (0.57) FTOHPGDHTTMEN1MAPT
SCHEMBL8571832 0.87 FTO (0.74) FTOHPGDHTTMEN1MAPT
SCHEMBL8571885 0.87 FTO (0.57) FTOHPGDHTTMEN1MAPT
SCHEMBL8567853 0.85 FTO (1.00) FTOHPGDHTTMEN1MAPT
SCHEMBL543293 0.83 FTO (1.00) FTOHPGDHTTMEN1MAPT
SCHEMBL4600340 0.83 FTO (0.79) FTOHPGDHTTMEN1MAPT
SCHEMBL29938908 0.83 FTO (1.00) FTOHPGDHTTMEN1MAPT
SCHEMBL8571847 0.82 FTO (0.51) FTOHPGDHTTMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240271178-A1 METHOD FOR DETECTION OF ESCHERICHIA COLI AND ANTIBIOTIC RESISTANT BACTERIA IN WATER Eastern Kentucky University (US) 2024-08-15 — — US claimed
EP-3206723-A1 BIOLOGICAL INDICATOR American Sterilizer Company (US) 2017-08-23 — — EP claimed
WO-2016060714-A1 BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY (US) 2016-04-21 — — WO claimed
US-20150024403-A1 METHOD FOR DETECTING REPLICATION OR COLONIZATION OF A BIOLOGICAL THERAPEUTIC GENELUX CORPORATION 2015-01-22 — — US claimed
US-8859256-B2 Method for detecting replication or colonization of a biological therapeutic GENELUX CORPORATION (US) 2014-10-14 — — US claimed
EP-2764119-A2 METHOD FOR DETECTING REPLICATION OR COLONIZATION OF A BIOLOGICAL THERAPEUTIC Genelux Corporation (US) 2014-08-13 — — EP claimed
US-20130130292-A1 Method for detecting replication or colonization of a biological therapeutic GENELUX CORPORATION 2013-05-23 — — US claimed
WO-2013052915-A2 METHOD FOR DETECTING REPLICATION OR COLONIZATION OF A BIOLOGICAL THERAPEUTIC GENELUX CORPORATION (US) 2013-04-11 — — WO claimed
US-20080176225-A1 DNA fragment encoding beta-glucuronidase; gene therapy; anticancer agents; cd antigens; immunoglobulins KAOHSIUNG MEDICAL UNIVERSITY (TW) 2008-07-24 — — US claimed
EP-1337658-B1 A METHOD FOR THE DETECTION OF VIABLE MICROORGANISMS BIOGEM OPTICAL LTD (IL) 2008-01-09 — — EP claimed
CN-100360682-C Method for detection of viable microorganisms BIOYEM LTD (IL) 2008-01-09 — — CN claimed
US-7312073-B2 Method for the detection of viable microorganisms BIOGEM OPTICAL LTD. (IL) 2007-12-25 — — US claimed
US-20050202523-A1 Method for the detection of viable microorganisms BIOGEM OPTICAL LTD. (IL) 2005-09-15 — — US claimed
CN-1481440-A Method for detection of viable microorganisms �ݿ��ù�ѧ���޹�˾ 2004-03-10 — — CN claimed
EP-1337658-A2 A METHOD FOR THE DETECTION OF VIABLE MICROORGANISMS Biogem Ltd. (IL) 2003-08-27 — — EP claimed
WO-2002038724-A2 A METHOD FOR THE DETECTION OF VIABLE MICROORGANISMS BIOGEM OPTICAL LTD (IL) 2002-05-16 — — WO claimed
US-20260115165-A1 INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE GENZYME CORP (US) 2026-04-30 — — US disclosed
US-12465586-B2 Inhibitors of glucosylceramide synthase GENZYME CORPORATION (US) 2025-11-11 — — US disclosed
US-20030003562-A1 Lactobacillus beta-glucuronidase and DNA encoding the same NORTH CAROLINA STATE UNIVERSITY 2003-01-02 — — US disclosed
US-5773236-A FLUORESCENT DYES FOR DETECTION OF ENZYMES FOR METABOLISM IN CELLS MOLECULE PROBES, INC. (US) 1998-06-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12465586-B2 Inhibitors of glucosylceramide synthase GBA1, UGCG, GBA2 FTO 1952/4885HPGD 717/4885HTT 227/4885
US-20260115165-A1 INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE UGCG, UGGT1, GBA1 FTO 870/4885HPGD 2026/4885HTT 1383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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