Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 3/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 14/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5097709 | 0.92 | PLA2G2A (0.47) | PLA2G2AALDH1A1MAPT | |
| SCHEMBL5093263 | 0.89 | SCN9A (0.43) | ALDH1A1MAPTSCN9A | |
| SCHEMBL5093351 | 0.88 | PLA2G2A (0.48) | PLA2G2AALDH1A1MAPT | |
| SCHEMBL5088628 | 0.88 | PLA2G2A (0.44) | PLA2G2AALDH1A1MAPTHPGD | |
| SCHEMBL5090593 | 0.87 | PLA2G2A (0.46) | PLA2G2A | |
| SCHEMBL5098634 | 0.85 | PLA2G2A (0.47) | PLA2G2AALDH1A1MAPT | |
| SCHEMBL5088597 | 0.84 | PLA2G2A (0.45) | PLA2G2AALDH1A1MAPTHPGD | |
| SCHEMBL5093321 | 0.84 | PLA2G2A (0.45) | PLA2G2AALDH1A1 | |
| SCHEMBL5093341 | 0.84 | MRGPRX4 (0.46) | PLA2G2AMAPT | |
| SCHEMBL5141934 | 0.83 | FFAR4 (0.45) | PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470708-B2 | Acidic quinoline derivatives and their use for the prevention and/or treatment of hyperglycaemia-related pathologies | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2008-12-30 | — | — | US | disclosed |
| US-7470708-B2 | Acidic quinoline derivatives and their use for the prevention and/or treatment of hyperglycaemia-related pathologies | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2008-12-30 | — | — | US | disclosed |
| US-7470708-B2 | Acidic quinoline derivatives and their use for the prevention and/or treatment of hyperglycaemia-related pathologies | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2008-12-30 | — | — | US | disclosed |