Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 13/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | SCN7A | Q01118 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5097666 | 0.91 | PPARA (0.42) | SCN9AALDH1A1KCNH2 | |
| SCHEMBL5088461 | 0.89 | PLA2G2A (0.43) | SCN9AALDH1A1MAPT | |
| SCHEMBL5088616 | 0.86 | MEN1 (0.44) | ALDH1A1KCNH2 | |
| SCHEMBL5098762 | 0.86 | KDM4E (0.43) | SCN9AALDH1A1KCNH2 | |
| SCHEMBL5088654 | 0.83 | CYSLTR1 (0.45) | KCNH2 | |
| SCHEMBL5088530 | 0.83 | DHODH (0.42) | ALDH1A1MAPT | |
| SCHEMBL5097669 | 0.83 | PPARG (0.53) | — | |
| SCHEMBL5093352 | 0.81 | ALOX15 (0.41) | SCN9AALDH1A1 | |
| SCHEMBL5097600 | 0.80 | ALOX15 (0.42) | ALDH1A1 | |
| SCHEMBL4649127 | 0.80 | ALOX15 (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470708-B2 | Acidic quinoline derivatives and their use for the prevention and/or treatment of hyperglycaemia-related pathologies | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2008-12-30 | — | — | US | disclosed |
| US-7470708-B2 | Acidic quinoline derivatives and their use for the prevention and/or treatment of hyperglycaemia-related pathologies | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2008-12-30 | — | — | US | disclosed |
| US-7470708-B2 | Acidic quinoline derivatives and their use for the prevention and/or treatment of hyperglycaemia-related pathologies | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2008-12-30 | — | — | US | disclosed |