SCHEMBL5088933

SCHEMBL5088933

[c]1cc2ccccc2nc1-c1cccc2nccnc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.39
KDM4E B2RXH2 4/20 0.39
ALDH1A1 P00352 3/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
POLB P06746 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 2/20 0.33
HTT P42858 2/20 0.33
TOP1 P11387 1/20 0.33
GMNN O75496 1/20 0.33
TP53 P04637 1/20 0.33
HSP90AA1 P07900 1/20 0.33
MMP2 P08253 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MMP9 P14780 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
NFKB1 P19838 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6448031 0.76 ALDH1A1 (0.43) MAPTKDM4EALDH1A1LMNAHTT
SCHEMBL3422756 0.76 CYP1A2 (0.54) MAPTKDM4EALDH1A1TP53CYP3A4
SCHEMBL3069598 0.73 KDM4E (0.58) MAPTKDM4EALDH1A1MEN1USP2
SCHEMBL382679 0.69 RAB9A (0.47) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL15511526 0.69 MAPT (0.46) MAPTKDM4EALDH1A1MEN1USP2
SCHEMBL2996550 0.69 PDE10A (0.40) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL2801515 0.69 TOP1 (0.53) MAPTKDM4EALDH1A1MEN1USP2
SCHEMBL16720376 0.68 NPC1 (0.50) MAPTKDM4EALDH1A1MEN1POLB
SCHEMBL16720319 0.68 TGFBR1 (0.52) KMT2AGSK3BCDK5CDK5R1
SCHEMBL3986805 0.68 NPC1 (0.59) MAPTKDM4EALDH1A1MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10071371-B2 Compositions and methods for reducing atmospheric ozone levels AIR CROSS INC (US) 2018-09-11 US disclosed
US-20170320052-A1 COMPOSITIONS AND METHODS FOR REDUCING ATMOSPHERIC OZONE LEVELS AIR CROSS INC (US) 2017-11-09 US disclosed
EP-3177398-A1 COMPOSITIONS AND METHODS FOR REDUCING ATMOSPHERIC OZONE LEVELS Duke, Christopher (US) 2017-06-14 EP disclosed
US-9669401-B2 Compositions and methods for reducing atmospheric ozone levels AIR CROSS INC (US) 2017-06-06 US disclosed
WO-2016023015-A1 COMPOSITIONS AND METHODS FOR REDUCING ATMOSPHERIC OZONE LEVELS Air Cross, Inc. (US) 2016-02-11 WO disclosed
US-20160038931-A1 COMPOSITIONS AND METHODS FOR REDUCING ATMOSPHERIC OZONE LEVELS AIR CROSS INC (US) 2016-02-11 US disclosed
US-7361763-B2 Pyrrolo-pyridine kinase modulators SGX PHARMACEUTICALS, INC. (US) 2008-04-22 US disclosed