Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.43 |
| ▸ | DHFR | P00374 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | C1S | P09871 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309910 | 0.84 | RAB9A (0.50) | KCNH2DHFRDPP4C1SADRB1 | |
| SCHEMBL14191683 | 0.83 | FBP1 (0.39) | KCNH2DPP4MAPTALDH1A1KDM4E | |
| SCHEMBL5139008 | 0.81 | KCNH2 (0.39) | KCNH2DHFRDPP4MAPTKDM4E | |
| SCHEMBL992823 | 0.80 | DPP4 (0.51) | KCNH2DHFRDPP4C1SADRB1 | |
| SCHEMBL14191682 | 0.79 | HTR2A (0.41) | KCNH2MAPTALDH1A1KDM4E | |
| SCHEMBL9310603 | 0.79 | KCNH2 (0.47) | KCNH2DHFRDPP4ADRB1MAPT | |
| SCHEMBL9312087 | 0.75 | KCNH2 (0.46) | KCNH2DHFRDPP4C1SADRB1 | |
| SCHEMBL9312192 | 0.73 | KCNH2 (0.53) | KCNH2DHFRDPP4C1SADRB1 | |
| SCHEMBL9310505 | 0.72 | DPP4 (0.43) | KCNH2DHFRDPP4C1SADRB1 | |
| Hydrochloric Acid SCHEMBL9311875 | 0.72 | C1S (0.51) | KCNH2DHFRDPP4C1SADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371755-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2008-05-13 | — | — | US | disclosed |
| EP-1214317-A1 | ANTIVIRAL AGENTS | BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001019822-A1 | ANTIVIRAL AGENTS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2001-03-22 | — | — | WO | disclosed |