Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.51 |
| ▸ | DDO | Q99489 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | IL4I1 | Q96RQ9 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30355103 | 0.87 | MAPK1 (0.51) | KDM4EALDH1A1HPGDHSD17B10DAO | |
| SCHEMBL17618004 | 0.86 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| Hydrochloric Acid SCHEMBL17601025 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL8797241 | 0.83 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL13349416 | 0.83 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL1263927 | 0.80 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL31154599 | 0.80 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL7646960 | 0.80 | DAO (0.53) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL1370758 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL4437503 | 0.79 | MAPK1 (0.58) | KDM4EALDH1A1HPGDHSD17B10DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351531-B2 | Molecules capable of binding to telomere and the like and method with the use of the same | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2008-04-01 | — | — | US | disclosed |
| EP-1164202-B1 | MISMATCH-RECOGNIZING MOLECULES | JAPAN SCIENCE & TECH AGENCY (JP) | 2006-06-07 | — | — | EP | disclosed |
| US-20040170980-A1 | Molecules capable of binding to telomere and the like and method with the use of the same | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-09-02 | — | — | US | disclosed |
| US-6607890-B1 | Base pairs, mimetics; kits; use to determine/identify a mismatched base pair in a nucleic acid such as DNA or RNA | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2003-08-19 | — | — | US | disclosed |
| EP-1302472-A1 | MOLECULES CAPABLE OF BINDING TO TELOMERE AND THE LIKE AND METHOD WITH THE USE OF THE SAME | Japan Science and Technology Corporation (JP) | 2003-04-16 | — | — | EP | disclosed |
| EP-1164202-A1 | MISMATCH-RECOGNIZING MOLECULES | Japan Science and Technology Corporation (JP) | 2001-12-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040170980-A1 | Molecules capable of binding to telomere and the like and method with the use of the same | TERT, LIG1, TELO2 | KDM4E 3602/4885ALDH1A1 1209/4885HPGD 3900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.