SCHEMBL5089520

SCHEMBL5089520

CON(CC(=O)O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
TSHR P16473 2/20 0.42
GLA P06280 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
MTNR1A P48039 2/20 0.41
MTNR1B P49286 2/20 0.41
MAPK1 P28482 1/20 0.41
NPSR1 Q6W5P4 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
KMT2A Q03164 2/20 0.39
POLB P06746 2/20 0.39
MEN1 O00255 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
NPC1 O15118 1/20 0.38
HTT P42858 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8021970 1.00 ALDH1A1 (0.42) ALDH1A1TSHRGLASMN1; SMN2MTNR1A
Ethylamine SCHEMBL28630883 0.93 TSHR (0.42) ALDH1A1TSHRGLASMN1; SMN2MTNR1A
SCHEMBL8704299 0.86 MTNR1A (0.43) ALDH1A1TSHRGLASMN1; SMN2MTNR1A
SCHEMBL8698622 0.83 ALDH1A1 (0.46) ALDH1A1TSHRSMN1; SMN2MAPK1NPSR1
SCHEMBL28961752 0.81 ALDH1A1 (0.40) ALDH1A1TSHRGLASMN1; SMN2MTNR1A
SCHEMBL27576865 0.81 ALDH1A1 (0.44) ALDH1A1TSHRGLASMN1; SMN2NPSR1
SCHEMBL28871165 0.81 MTNR1A (0.46) ALDH1A1TSHRGLASMN1; SMN2MTNR1A
SCHEMBL8011282 0.80 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2MTNR1AMTNR1BKMT2A
SCHEMBL10779297 0.79 ALDH1A1 (0.41) ALDH1A1TSHRGLASMN1; SMN2
SCHEMBL26670322 0.78 TDP1 (0.44) ALDH1A1TSHRGLASMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110357989-A Tertiary amine photosensitizer, preparation method, comprising its photosensitive polymer combination and photosensitive polymer combination application 常州强力电子新材料股份有限公司 2019-10-22 CN claimed
US-20230365628-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL-MYERS SQUIBB COMPANY (US) 2023-11-16 US disclosed
US-20230022400-A1 IMMUNOMODULATORS BRISTOL MYERS SQUIBB CO (US) 2023-01-26 US disclosed
CN-110357989-B Tertiary amine photosensitizer, preparation method thereof, photosensitive resin composition containing tertiary amine photosensitizer and application of photosensitive resin composition 常州强力电子新材料股份有限公司 2022-04-22 CN disclosed
US-10808150-B2 Resin composition, method for manufacturing semiconductor device using resin composition, and solid-state imaging element HITACHI CHEMICAL COMPANY, LTD. (JP) 2020-10-20 US disclosed
CN-110357989-A Tertiary amine photosensitizer, preparation method, comprising its photosensitive polymer combination and photosensitive polymer combination application 常州强力电子新材料股份有限公司 2019-10-22 CN disclosed
US-10358580-B2 Adhesive composition, resin cured product obtained from adhesive composition, method for manufacturing semiconductor device using adhesive composition, and solid-state imaging element HITACHI CHEMICAL COMPANY, LTD. (JP) 2019-07-23 US disclosed
US-20180208807-A1 RESIN COMPOSITION, METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE USING RESIN COMPOSITION, AND SOLID-STATE IMAGING ELEMENT RESONAC CORPORATION (JP) 2018-07-26 US disclosed
CN-108017558-A A kind of preparation method of anise nitrile 河南省洛阳水文水资源勘测局 2018-05-11 CN disclosed
CN-107849417-A Adhesive composite, solidfied material, semiconductor device and its manufacture method 日立化成株式会社 2018-03-27 CN disclosed
US-9920227-B2 Resin composition, method for manufacturing semiconductor device using resin composition, and solid-state imaging element HITACHI CHEMICAL COMPANY, LTD. (JP) 2018-03-20 US disclosed
US-9868884-B2 Adhesive composition, method for manufacturing semiconductor device using adhesive composition, and solid-state imaging element HITACHI CHEMICAL COMPANY, LTD. (JP) 2018-01-16 US disclosed
US-20160355709-A1 RESIN COMPOSITION, METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE USING RESIN COMPOSITION, AND SOLID-STATE IMAGING ELEMENT RESONAC CORPORATION (JP) 2016-12-08 US disclosed
US-20160340554-A1 ADHESIVE COMPOSITION, RESIN CURED PRODUCT OBTAINED FROM ADHESIVE COMPOSITION, METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE USING ADHESIVE COMPOSITION, AND SOLID-STATE IMAGING ELEMENT RESONAC CORPORATION (JP) 2016-11-24 US disclosed
US-20160340561-A1 ADHESIVE COMPOSITION, METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE USING ADHESIVE COMPOSITION, AND SOLID-STATE IMAGING ELEMENT HITACHI CHEMICAL COMPANY, LTD. (JP) 2016-11-24 US disclosed
CN-105934491-A Adhesive composition, method for manufacturing semiconductor device using adhesive composition, and solid-state imaging element 日立化成株式会社 2016-09-07 CN disclosed
CN-105934478-A Resin composition, method for manufacturing semiconductor device using resin composition, and solid-state imaging element 日立化成株式会社 2016-09-07 CN disclosed
CN-105934488-A Adhesive composition, cured resin obtained from adhesive composition, method for manufacturing semiconductor device using adhesive composition, and solid-state imaging element 日立化成株式会社 2016-09-07 CN disclosed
WO-2008101840-A1 COMBINATION OF ERLOTINIB AND MEK-INHIBITORS FOR INHIBITING PROLIFERATION OF TUMOR CELLS F. HOFFMANN-LA ROCHE AG (CH) 2008-08-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230022400-A1 IMMUNOMODULATORS CD274, PDCD1LG2, PDCD1 ALDH1A1 1602/4885TSHR 2165/4885GLA 3805/4885
US-20230365628-A1 MACROCYCLIC IMMUNOMODULATORS CD274, PDCD1, PDCD1LG2 ALDH1A1 3750/4885TSHR 1024/4885GLA 4196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.